In Silico Structure‐Guided Design of Peptide Candidates Targeting γ‐Secretase Subunit Assembly
ABSTRACT The γ‐secretase complex is a membrane‐embedded protease essential for intramembrane cleavage of substrates such as Notch receptors and the amyloid precursor protein (APP), processes central to cancer progression and Alzheimer's disease (AD) pathology.
Selcen Arı Yuka +2 more
wiley +1 more source
Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE@home) for Adults With Chronic Stroke: Protocol for a Randomized Controlled Trial. [PDF]
Somville M +5 more
europepmc +1 more source
Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz +7 more
wiley +1 more source
Interaction with CYP20-3 limits OPDA flux into jasmonate biosynthesis in wounded leaves of arabidopsis grown at eCO<sub>2</sub>. [PDF]
Redl A, Gabriel J, van Dam NM, Bede JC.
europepmc +1 more source
Modulation of wind drag by tidal currents in an embayment
Tidal currents modulate how wind energy enters the surface wave field by influencing both wave drag and wave generation. In Shark Bay, following currents reduce effective wave steepness and wind drag, and opposing currents enhance wave growth. Wind energy is partitioned between wave drag and the creation of new waves, explaining observed tidal ...
Stephen M. Thurgate +1 more
wiley +1 more source
Solution-state nuclear magnetic resonance studies of the <i>Salmonella typhimurium</i> tryptophan synthase complex. [PDF]
D'Amico RN +3 more
europepmc +1 more source
ABSTRACT The dynamic nature of small islands being geographically isolated and their perceived connectedness with global networks complicates research attempts to draw general conclusions on whether insularity leads to marginalization or strengthens their resilience for sustainable development.
Toheeb Lekan Jolaosho +2 more
wiley +1 more source
Construction of Escherichia coli L-isoleucine cell factories based on propionate pathway. [PDF]
Xiao Y +5 more
europepmc +1 more source
DSM-5: Il buono, il cattivo, il brutto [PDF]
openaire +2 more sources
Environmental Footprint of Diffuse Emissions in European Functional Urban Areas
ABSTRACT This paper quantifies the environmental footprint of diffuse air emissions across 776 European functional urban areas (FUAs) from 2005 to 2022 by coupling Copernicus Atmosphere Monitoring Service (CAMS) gridded inventories with the Environmental Footprint (EF) 3.1 framework.
Iñaki Sasia, Gorka Bueno, Iker Etxano
wiley +1 more source

