NOD2 and inflammation: current insights [PDF]
, 2018 The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory ...
Cucchiara, Salvatore +3 more
core +2 more sources
Ileal Crohn's disease: MRI with endoscopic correlation
European Journal of Radiology, 2011 To evaluate activity staging of Crohn's disease (CD) measured with MR-enterography using ileoscopy as reference standard.A prospective study was made of 61 patients with CD. All patients underwent MR-enterography and ileoscopy. MRI activity was measured by means of an ad hoc developed score, as well as by analysis of the imaging findings, and was ...
Gallego, José C. +3 more
openaire +3 more sources
Switching from a protease inhibitor-based regimen to a dolutegravir-based regimen : a randomized clinical trial to determine the effect on peripheral blood and ileum biopsies from antiretroviral therapy-suppressed human immunodeficiency virus-infected individuals [PDF]
, 2018 Background: Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted ...
Blanco, Julià +15 more
core +3 more sources
Endometriosis of the Terminal Ileum: A Diagnostic Dilemma
Case Reports in Pathology, 2012 Endometriosis is characterized by the presence of endometrial tissue consisting of glands and/or stroma located outside the uterus. Involvement of the terminal ileum is extremely rare.
Kerem Karaman +6 more
doaj +1 more source
Ileal pouch-anal anastomosis for Crohn's disease
Gut, 1999 Editor,—In his leading article ( Gut 1998; 43 :303–8), Mr Phillips makes a plea for realistic comparisons between outcomes for pouch surgery in Crohn’s disease with other restorative procedures for this disease, rather than comparisons with restorative …
C M EDWARDS, B F WARREN, N A SHEPHERD
openaire +4 more sources
Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota. [PDF]
, 2014 Periodontitis has been implicated as a risk factor for metabolic disorders such as type 2 diabetes, atherosclerotic vascular diseases, and non-alcoholic fatty liver disease. Although bacteremias from dental plaque and/or elevated circulating inflammatory
Arimatsu, Kei +10 more
core +2 more sources
BMC Veterinary Research, 2008 Backgound In scrapie and prion diseases, the knowledge concerning genes involved in host response during the early infection period in the lymphoid tissues, still remains limited.
Olsaker Ingrid +5 more
doaj +1 more source
Uretero-ileal fistula due to Crohn's disease
Journal of British Surgery, 1971 Abstract The literature is briefly reviewed and the rarity of uretero-ileal fistulas confirmed. A case of right-sided uretero-ileal fistula associated with Crohn's disease is described.
L H, Blumgart, K, Thakur
openaire +2 more sources
Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
, 2016 Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core +1 more source
Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways [PDF]
, 2017 Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of ...
Cecilia Giulivi +12 more
core +3 more sources