Results 51 to 60 of about 35,795 (270)

Ileal Crohn's disease is best treated by surgery [PDF]

Gut, 2002
Burrill Crohn et al in 1932 stated that “medical therapy is purely palliative and supportive . . ... but in general the proper approach to complete cure is by surgical resection . . ..”. However, by 1987 Bryan Brooke, a committed and creative inflammatory bowel disease surgeon, recognised that “the surgical stance is now one of reluctance ...
openaire   +5 more sources

Morphology of ileal and jejunal pouches used as rectal substitutes

, 2003
PURPOSE: Our aim was to determine whether the mucosa of a canine jejunal pouch used as a rectal substitute after proctocolectomy retains its morphologic features better than the mucosa of a canine ileal pouch so used.
Teixeira, Fabio V., Eleuterio, Maria L., Silva, Maeli D. P. [UNESP], Daud, Danilo, Silva, Maeli D. P., Kelly, Keith A.   +5 more
core   +1 more source

Early weaning stress in pigs impairs innate mucosal immune responses to enterotoxigenic E. coli challenge and exacerbates intestinal injury and clinical disease. [PDF]

PLoS ONE, 2013
The clinical onset and severity of intestinal disorders in humans and animals can be profoundly impacted by early life stress. Here we investigated the impact of early weaning stress in pigs on intestinal physiology, clinical disease, and immune response
Brittney L McLamb, Amelia J Gibson, Elizabeth L Overman, Chad Stahl, Adam J Moeser   +4 more
doaj   +1 more source

Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice

Microbiome, 2023
Background Intestinal epithelial cell (IEC) mitochondrial dysfunction involvement in inflammatory bowel diseases (IBD), including Crohn’s disease affecting the small intestine, is emerging in recent studies.
Kibrom M. Alula, Alexander S. Dowdell, Brittany LeBere, J. Scott Lee, Cassandra L. Levens, Kristine A. Kuhn, Benny A. Kaipparettu, Winston E. Thompson, Richard S. Blumberg, Sean P. Colgan, Arianne L. Theiss   +10 more
doaj   +1 more source

Uretero-ileal fistula due to Crohn's disease

Journal of British Surgery, 1971
Abstract The literature is briefly reviewed and the rarity of uretero-ileal fistulas confirmed. A case of right-sided uretero-ileal fistula associated with Crohn's disease is described.
L H, Blumgart, K, Thakur
openaire   +2 more sources

Intestinal microbiota in human health and disease: the impact of probiotics [PDF]

, 2011
The complex communities of microorganisms that colonise the human gastrointestinal tract play an important role in human health. The development of culture-independent molecular techniques has provided new insights in the composition and diversity of the
Gerritsen, J., Vos, W.M., de, Ger T. Rijkers, Smidt, H., Jacoline Gerritsen, Rijkers, G.T., Willem M. de Vos, Hauke Smidt, de Vos, W.M.   +8 more
core   +1 more source

Rare presentations of small bowel endometriosis

DEN Open
Despite endometriosis being a relatively common chronic gynecological condition in women of childbearing age, small bowel endometriosis is rare. Presentations can vary from completely asymptomatic to reported symptoms of abdominal pain, bloating, and ...
Anthony Sakiris, Ezaam Naik Fraz, Arvinf Rajandran, Jason Smith, Benjamin Allen, Sooraj Pillai, Pradeep Kakkadasam Ramaswamy, Sneha John   +7 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Ileocolic Intussusception in Adults: A Rare Presentation of an Underlying Malignancy

Acta Médica Portuguesa
N ...
Catarina Rolo Santos, Frederico Nazareth, Zara Maria Caetano   +2 more
doaj   +1 more source

Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson’s disease

Nature Communications, 2023
Inflammation in the brain and gut is a critical component of several neurological diseases, such as Parkinson’s disease (PD). One trigger of the immune system in PD is aggregation of the pre-synaptic protein, α-synuclein (αSyn).
Rhonda L. McFleder, Anastasiia Makhotkina, Janos Groh, Ursula Keber, Fabian Imdahl, Josefina Peña Mosca, Alina Peteranderl, Jingjing Wu, Sawako Tabuchi, Jan Hoffmann, Ann-Kathrin Karl, Axel Pagenstecher, Jörg Vogel, Andreas Beilhack, James B. Koprich, Jonathan M. Brotchie, Antoine-Emmanuel Saliba, Jens Volkmann, Chi Wang Ip   +18 more
doaj   +1 more source