Results 121 to 130 of about 199,284 (357)

Effects of Dietary Protein Level on Growth Performance, Serum Biochemistry, Intestinal Morphology, and Intestinal Microbiota in Ningxiang Finishing Pigs

Animal Research and One Health, EarlyView.
A low‐protein (LP) diet maintained growth performance while enhancing colonic microbiota composition and nitrogen utilization in Ningxiang finishing pigs. These findings enhance our understanding of protein nutrition in indigenous fat‐type pig breeds and provide a theoretical foundation for optimizing dietary formulations in Ningxiang pigs.
Xianglin Zeng, Wenzhi Liu, Zhaobin Wang, Kai Yang, Qiye Wang, Huansheng Yang   +5 more
wiley   +1 more source

Gut Microbiome Revealed the Dominant Microbes Affecting the Feed Efficiency of Wannan Yellow Chicken

Brazilian Journal of Poultry Science
Intestinal digestibility can be affected by the interaction between host and gut microbiota, which could influence feed efficiency in poultry. In this study, the performance of 1480 10-week-old Wannan Yellow chickens was recorded for 6 weeks, and the ...
Ji Q, He K, Peng J, Chang P, Zhu X, Geng Z, Chen X   +6 more
doaj   +1 more source

Intestine‐Specific Expression of Human Chimeric Intestinal Alkaline Phosphatase Attenuates Western Diet‐Induced Barrier Dysfunction and Glucose Intolerance [PDF]

, 2018
Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen.
Ghosh, Shobha, Ghosh, Siddhartha S., He, Hongliang, Korzun, William, Wang, Jing, Yannie, Paul J.   +5 more
core   +1 more source

The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]

, 2008
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J., Beigel, Florian, Brand, Stephan, Dambacher, J., Diepolder, Helmut M., Göke, Burkhard, Toni, Enrico N. de, Zitzmann, K.   +7 more
core   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Ileal bile acid transporter inhibitors in Alagille syndrome and Progressive Familial Intrahepatic Cholestasis: A systematic review into dose–response

British Journal of Clinical Pharmacology, EarlyView.
Ileal bile acid transporter inhibitors (IBATi), including maralixibat and odevixibat, are a novel approach to the treatment of paediatric cholestatic liver diseases, such as Alagille syndrome (ALGS) and different forms of progressive familial intrahepatic cholestasis (PFIC).
Alise D. E. de Groot, Cristina Chiadò, Jos G. W. Kosterink, Willem S. Lexmond, Paola Mian, Henkjan J. Verkade   +5 more
wiley   +1 more source

Synchronous ectopic gastric mucosa in an infant with Meckel′s diverticulum and lower gastrointestinal bleed

Journal of Indian Association of Pediatric Surgeons, 2007
A 7-months-old male child presented with severe lower gastrointestinal bleeding. His radionuclide scan showed ectopic gastric mucosa in Meckel′s diverticulum as well as in distal ileum. On exploration a 5 cm indurated bleeding ulcer found in ileum
Sharma S, Debnath P, Tripathi R, Mishra A, Deori P, Agrawal L   +5 more
doaj  

Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter‐Mediated Interactions Using a Human Primary Intestinal 3D Model (EpiIntestinal™)

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate prediction of oral drug absorption in humans is essential for early drug development; however, physiologically relevant human models are lacking. This study aims to comprehensively assess the EpiIntestinal™, a human primary intestinal 3D model, for its ability to predict oral absorption (Fa), intestinal availability (Fg), CYP3A4 induction, and
Paresh P. Chothe, Andrea Whitcher‐Johnstone, Aniruddha Karve, Diane Ramsden, Niresh Hariparsad   +4 more
wiley   +1 more source

The intestinal expulsion of the roundworm Ascaris suum is associated with eosinophils, intra-epithelial T cells and decreased intestinal transit time [PDF]

, 2013
Ascaris lumbricoides remains the most common endoparasite in humans, yet there is still very little information available about the immunological principles of protection, especially those directed against larval stages.
A Fujiwara, A Roepstorff, A Zhao, A Zhao, Aaron R. Jex, BA Vallance, C Dold, C Moolenbeek, C Zhou, CD Criscione, CV Holland, D Leles, D Masure, Dries Masure, DW Crompton, F van Wijk, G Jungersen, GH Liu, HD Dawson, J Vandesompele, JF Urban Jr, Jimmy Saunders, Johnny Vlaminck, Jozef Vercruysse, KD Mccoy, Koen Chiers, L Eriksen, M Ashraf, M Morimoto, N Arizono, N Foster, N Miquel, NL Harris, P Kermanizadeh, P Nejsum, P O'Lorcain, PA Knight, Peter Geldhof, PI Uston, R Shamri, RM Anthony, RW Li, S Rozen, S Schmidt, Sarah Claerhoudt, Tao Wang, TB Stewart, TJ Anderson, Wim Van den Broeck   +48 more
core   +4 more sources

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

Clinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren, Jing An, Wei Chen, Jiao Li, Xing Li, Anning Yin, Jing Wang, Wei Wang, Jingyun Cheng, Jian Kang, Yaqing Xu, Yueyue Lu, Juan Su, Qian Zhou, Huipeng Wan, Zimeng Zhang, Ping An   +16 more
wiley   +1 more source