Results 161 to 170 of about 700,365 (275)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Methodological Assessment of High-Throughput Sequencing Platforms: Illumina vs. MGI in Clinical-Grade <i>CFTR</i> Genotyping. [PDF]

Int J Mol Sci
Beggio M, Peroni E, Greco E, Favretto G, Degiorgio D, Rosato A, Favarato M.   +6 more
europepmc   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

P226: Genome sequencing after negative exome sequencing: Results in a rare disease cohort

Genetics in Medicine Open
Keri Ramsey, Newell Belnap, Marcus Naymik, Anna Bonfitto, Meredith Sanchez-Castillo, Matthew Huentelman, Vinodh Narayanan, Akanchha Kesari, Dianne Hernandez, Richard Wang, Samuel Strom, Krista Bluske, Anjana Chandrasekhar, Joshua Lowry, Sylwia Urbaniak, Michael Pham, Jon Albay, Ryan Taft, Ali Crawford   +18 more
doaj   +1 more source

Optimizing data-driven excellence: Canada's approach to using pathogen test datasets for quality control, pipeline development and training initiatives. [PDF]

Microb Genom
Loos KD, Horsman M, Tuff J, Kamelian K, Hole D, Yadav C, Palmier K, Burak K, Pratt M, Chato C, Majer A, Tyson S, Seo GE, Mabon P, Grudeski E, Huzarewich R, Mandes R, Landgraff A, Tanner JR, Knox N, Graham M, Van Domselaar G, Minion J, Bastien N, Booth T, Chapel M, Biggar K, Duggan A, Yoshida C, Tyler A.   +29 more
europepmc   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

The Chromosome-Scale Genome Assembly of the Redlip Blenny, Ophioblennius macclurei (Blenniidae). [PDF]

Genome Biol Evol
Kulikov N, Joffroy K, Bonacolta AM, Del Campo J, Irisarri I.   +4 more
europepmc   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

P707: Systematic reanalysis of clinical genome sequencing data in a cohort of acute care patients

Genetics in Medicine Open
Aditi Chawla, Samuel Strom, Brittany Thomas, Samin Sajan, Qing Zhang, Akanchha Kesari, Maren Bennett, Keisha Robinson, Denise Perry, Subramanian Ajay, Shay Tzur, Ryan Taft, Tasha Kalista   +12 more
doaj   +1 more source

Complete genome of a <i>Corynebacterium ulcerans</i> clinical isolate with two novel toxin gene alleles isolated from a leg ulcer. [PDF]

Microbiol Resour Announc
Bernier A-M, Unger M, Burdz T, Tanner JR.   +3 more
europepmc   +1 more source