Results 91 to 100 of about 411,747 (263)

Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing. [PDF]

PLoS Comput Biol, 2023
Wick RR, Judd LM, Holt KE.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Improved hybrid de novo genome assembly and annotation of African wild rice, Oryza longistaminata , from Illumina and PacBio sequencing reads

, 2020
Wei Li, Kui Li, Qun‐Jie Zhang, Ting Zhu, Yun Zhang, Cong Shi, Yunlong Liu, Enhua Xia, Jianjun Jiang, Chao Shi, Liping Zhang, Hui Huang, Yan Tong, Yuan Liu, Dan Zhang, Yuan Zhao, Wenkai Jiang, Youjie Zhao, Shu‐Yan Mao, Jun-Ying Jiao, Ping‐zhen Xu, Lili Yang, Guoying Yin, Lizhi Gao   +23 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Changes in the Soil Microbiome in Eggplant Monoculture Revealed by High-Throughput Illumina MiSeq Sequencing as Influenced by Raw Garlic Stalk Amendment [PDF]

, 2019
Muhammad Imran Ghani, Ahmad Ali, Muhammad Jawaad Atif, Muhammad Ali, Bakht Amin, Muhammad Anees, Haris Khurshid, Zhihui Cheng   +7 more
openalex   +1 more source

Investigation of Gut Microbiota Disorders in Sepsis and Sepsis Complicated with Acute Gastrointestinal Injury Based on 16S rRNA Genes Illumina Sequencing. [PDF]

Infect Drug Resist, 2023
Zuo Z, Pei L, Liu T, Liu X, Chen Y, Hu Z.   +5 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Evaluation of somatic copy number variation detection by NGS technologies and bioinformatics tools on a hyper-diploid cancer genome

Genome Biology
Background Copy number variation (CNV) is a key genetic characteristic for cancer diagnostics and can be used as a biomarker for the selection of therapeutic treatments.
Daniall Masood, Luyao Ren, Cu Nguyen, Francesco G. Brundu, Lily Zheng, Yongmei Zhao, Erich Jaeger, Yong Li, Seong Won Cha, Aaron Halpern, Sean Truong, Michael Virata, Chunhua Yan, Qingrong Chen, Andy Pang, Reyes Alberto, Chunlin Xiao, Zhaowei Yang, Wanqiu Chen, Charles Wang, Frank Cross, Severine Catreux, Leming Shi, Julia A. Beaver, Wenming Xiao, Daoud M. Meerzaman   +25 more
doaj   +1 more source

An Illumina MiSeq sequencing-based method using the mreB gene for high-throughput discrimination of Pseudomonas species in raw milk

, 2022
Zeyu Ren, Nan Li, Leilei Yu, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai   +6 more
openalex   +1 more source

Illumina sequencing data of the complete chloroplast genome of rare species Juniperus seravschanica (Cupressaceae) from Kazakhstan. [PDF]

Data Brief, 2023
Yermagambetova M, Abugalieva S, Turuspekov Y, Almerekova S.   +3 more
europepmc   +1 more source