Results 81 to 90 of about 463,626 (303)
Frontiers in Pharmacology, 2023 Introduction: Metagenomic next-generation sequencing (mNGS) has been increasingly used to detect infectious organisms and is rapidly moving from research to clinical laboratories.
Shuangyu Han +5 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Reliable variant calling during runtime of Illumina sequencing [PDF]
Scientific Reports, 2018 Abstract The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequencing process.
Loka, Tobias P. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
leeHom: adaptor trimming and merging for Illumina sequencing reads [PDF]
Nucleic Acids Research, 2014 Abstract The sequencing of libraries containing molecules shorter than the read length, such as in ancient or forensic applications, may result in the production of reads that include the adaptor, and in paired reads that overlap one another.
Renaud, G. ; https://orcid.org/0000-0002-0630-027X +2 more
openaire +3 more sources
Summary of transcriptomes assembled by Illumina sequencing. [PDF]
, 2016 Summary of transcriptomes assembled by Illumina sequencing.
Shouwei Tang (397331) +4 more
core +1 more source
List of reconstructed plastome sequences from Illumina sequencing. [PDF]
, 2023 List of reconstructed plastome sequences from Illumina sequencing.
Olivier J. Hardy (8035205) +6 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Statistical summary of trimmed Illumina sequencing data. [PDF]
, 2014 Statistical summary of trimmed Illumina sequencing data.
Carla Cristina da Silva (601915) +7 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source