Results 81 to 90 of about 1,171,841 (304)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Removing noise from pyrosequenced amplicons [PDF]

, 2011
<b>Background</b><p></p> In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced.
Quince, Christopher, Marie Ollier, Decousus, Stephanie, Davenport, Russell J., Christopher Quince, Davenport Russell J, Quince Christopher, Ollier, Marie, Sandrine Viala, Saghir, Nagi,, Uhrhammer, Nancy, Saghir, Nagi, S El, Turnbaugh, Peter, Davenport, Russell J, Turnbaugh, Peter J., Lanzen Anders, Ponelle, Flora, Nancy Uhrhammer, Russell J Davenport, Lanzen, Anders, Uhrhammer, Nancy A., Axel Poulet, Privat, Maud, Peter J Turnbaugh, Maud Privat, Axel Perin, Lafarge, Laurence, Bidet, Yannick, Laurence Lafarge, Stephanie Decousus, Poulet, Axel, Viala, Sandrine, Yannick Bidet, Nagi S. El Saghir, Yves-Jean Bignon, Bignon, Yves-Jean, Turnbaugh Peter J, El-Saghir, Nagi S., Flora Ponelle, Anders Lanzen, Perin, Axel, Bignon, Yves Jean   +41 more
core   +1 more source

16S Illumina Sequencing of Aguamiel Microbiota

, 2022
Dataset of the 16S gene V4 region Illumina Sequencing of Agave salmiana sieve's (aguamiel) microbial ...
Huezo-Sánchez, Ana Rosa
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Hybrid Enterobacteriaceae assemblies using PacBio+Illumina or ONT+Illumina sequencing

, 2019
Data associated with: De Maio, Shaw, et al. on behalf of the REHAB consortium (2019), Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes. biorxiv 530824 Illumina sequencing allows rapid, cheap and accurate
Nicola De Maio (233448), Liam Shaw (5487083), The REHAB Consortium (6276655)   +2 more
core   +1 more source

VADER PylT Illumina sequencing data

, 2022
FASTQ files used in data analysis for "Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells."
openaire   +2 more sources

Illumina-based transcriptome sequencing of mussel Mytilus coruscus mantle

浙江大学学报. 农业与生命科学版, 2015
Mollusk shell is an exoskeleton made up of organic mineral particles and its function is to protect the inner soft body from predators and environmental damage. Due to its superior mechanical properties, such as stiffness, fracture toughness, and tensile
Bao Linfei, Wang Xinxing, He Jianyu, Fan Meihua, Gao Peng, Liao Zhi   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Serial Illumina Sequencing (SI-Seq).

, 2012
(A) Schematic of the 16S rRNA locus with the hypervariable regions indicated as cylinders. The V5 through V7 hypervariable regions are PCR amplified with using universal primers tagged with 8-mer barcodes on their 5′ ends. (B) Ligation of Illumina paired-
Pauline Fung (131308), Lijie Yuan (131313), David S. Guttman (131322), Sylva L. Donaldson (131312), David M. Hwang (131320), D. Elizabeth Tullis (131318), Heather Maughan (131299), Yu Zhang (12946), Shaf Keshavjee (131315), Pauline W. Wang (131303), Yunchen Gong (109044), Yvonne C. W. Yau (131316), Julio Diaz Caballero (131307), Valerie J. Waters (131317)   +13 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source