Results 91 to 100 of about 1,171,841 (304)

Plasmodium knowlesi Genome Sequences from Clinical Isolates Reveal Extensive Genomic Dimorphism. [PDF]

, 2015
Plasmodium knowlesi is a newly described zoonosis that causes malaria in the human population that can be severe and fatal. The study of P. knowlesi parasites from human clinical isolates is relatively new and, in order to obtain maximum information from
Sanderson, Theo, Scott B Millar, Theo, Sanderson, Janet Cox-Singh (218129), Janet Cox-Singh, Rayner, Julian C., Rayner, Julian C, Janet, Cox-Singh, Millar, SB, Sanderson Theo, Scott B. Millar (615592), Sanjeev Krishna (4917), Miguel M. Pinheiro (615585), Miguel M., Pinheiro, Pinheiro, MM, Sanjeev, Krishna, Ahmed, Md Atique, Lu Woon Chan, Millar Scott B., Md Atique Ahmed, Sanjeev Krishna, Monsanto Pinheiro, Miguel, Thomas, D. Otto, Millar, Scott B, Pinheiro Miguel M., Lu, Woon Chan, Thomas D. Otto (188722), Cox-Singh, J, Md Atique, Ahmed, Rayner Julian C., Theo Sanderson (5662720), Cox-Singh, Janet, Miguel M Pinheiro, Otto, Thomas D, Otto, TD, Otto, Thomas D., Scott B., Millar, Millar, Scott B., Cox-Singh Janet, Krishna Sanjeev, Lu, WC, Ahmed Md Atique, Julian C Rayner, Woon, Chan Lu, Woon Chan Lu (716048), Julian C., Rayner, Md Atique Ahmed (716047), Sanderson, T, Krishna, S, Krishna, Sanjeev, Otto Thomas D., Theo Sanderson, Rayner, JC, Pinheiro, Miguel M., Ahmed, MA, Julian C. Rayner (121198), Thomas D Otto, Woon Chan Lu   +57 more
core   +2 more sources

Addressing challenges in the production and analysis of illumina sequencing data [PDF]

BMC Genomics, 2011
Abstract Advances in DNA sequencing technologies have made it possible to generate large amounts of sequence data very rapidly and at substantially lower cost than capillary sequencing. These new technologies have specific characteristics and limitations that require either consideration during project design, or which must be addressed ...
Kircher, M., Heyn, P., Kelso, J. ; https://orcid.org/0000-0002-3618-322X   +2 more
openaire   +4 more sources

stilPCR increases the effective sequencing length of Illumina targeted next-generation sequencing.

PLoS ONE
Identifying pathogens, resistance-conferring mutations, and strain types through targeted amplicon sequencing is an important tool. However, due to the limitations of short read sequencing, many applications require the division of limited clinical ...
Jason D Limberis, Roland J Nagel, Soumitesh Chakravorty, Dena Block, Scott Dewell, Alina Nalyvayko, Zach Howard, Grant Theron, Rouxjeane Venter, John Z Metcalfe   +9 more
doaj   +1 more source

Nanopore duplex sequencing as an alternative to Illumina MiSeq sequencing for eDNA-based biomonitoring of coastal aquaculture impacts [PDF]

Metabarcoding and Metagenomics
Oxford Nanopore Technologies has recently launched a duplex sequencing strategy and announced an improved error rate which is in a similar order of magnitude as Illumina sequencing.
Thorsten Stoeck, Sven Nicolai Katzenmeier, Hans-Werner Breiner, Verena Rubel   +3 more
doaj   +3 more sources

Microbiome-based environmental monitoring of a dairy processing facility highlights the challenges associated with low microbial-load samples

npj Science of Food, 2021
Efficient and accurate identification of microorganisms throughout the food chain can potentially allow the identification of sources of contamination and the timely implementation of control measures.
Aoife J. McHugh, Min Yap, Fiona Crispie, Conor Feehily, Colin Hill, Paul D. Cotter   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

The First Insight into the Tissue Specific Taxus Transcriptome via Illumina Second Generation Sequencing

, 2011
The First Insight into the Tissue Specific Taxus Transcriptome via Illumina Second Generation SequencingBackground: Illumina second generation sequencing is now an efficient route for generating enormous sequence collections that represent expressed ...
Yang Ling, Da Cheng Hao, Ling Yang, Xiao PeiGen, Hao, Da Cheng, 杨凌, Hao Da Cheng, PeiGen Xiao, YanYan Zhang, Xiao, PeiGen, Zhang YanYan, Ge GuangBo, GuangBo Ge, Ge, GuangBo, Yang, Ling, Zhang, YanYan   +15 more
core   +1 more source

Genome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos) [PDF]

, 2011
Background Next generation sequencing technologies allow to obtain at low cost the genomic sequence information that currently lacks for most economically and ecologically important organisms. For the mallard duck genomic data is limited. The mallard is,
Kerstens Hindrik HD, van Hooft, W.F., van der Poel, J.J., Prins, Herbert HT, Robert HS Kraus, van Hooft, Pim, Kraus, R.H.S., Prins, Herbert H. T., Prins, H.H.T., Poel, J., Van Hooft Pim, Hooft, Pim Van, Li Ning, Jan J Van Der Poel, Johan Elmberg, Huang Yinhua, Prins Herbert HT, Elmberg, Johan, Vignal Alain, Martien AM Groenen, Crooijmans, Richard P. M. A., Elmberg Johan, Groenen, M.A.M., van Hooft, Pim,, Van Der Poel Jan J, Huang, Y., Kraus, Robert Hs, Pim Van Hooft, Vignal, Alain, Crooijmans, R.P.M.A., Yinhua Huang, Groenen, Martien A. M., Vignal, Alain,, Li, N., Crooijmans, R., Kerstens, H., Crooijmans, Richard P. M. A.,, Herbert HT Prins, Elmberg, J., Groenen, M., Kerstens, Hindrik HD, Elmberg, Johan,, Kraus, Robert, Groenen, Martien AM, Prins, Herbert H. T.,, Kraus Robert HS, Prins, H., Huang, Yinhua,, Groenen Martien AM, Poel, J.J., van der, Kersten, H.H.D., van der Poel, Jan J., Li, Ning, Kraus, Robert H. S.,, Kraus, Robert H. S., Huang, Yinhua, Hooft, W.F., van, Crooijmans, Richard PMA, Kerstens, Hindrik H. D.,, Kerstens, Hindrik H. D., Li, Ning,, Hooft, P., Hindrik HD Kerstens, Richard PMA Crooijmans, Vignal, A., Alain Vignal, Kraus, R., Groenen, Martien A. M.,, Ning Li, Crooijmans Richard PMA, van der Poel, Jan J.,   +70 more
core   +2 more sources

Metagenomic data for Halichondria panicea from Illumina and nanopore sequencing and preliminary genome assemblies for the sponge and two microbial symbionts

BMC Research Notes, 2022
Objectives These data were collected to generate a novel reference metagenome for the sponge Halichondria panicea and its microbiome for subsequent differential expression analyses.
Brian W. Strehlow, Astrid Schuster, Warren R. Francis, Donald E. Canfield   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source