Results 1 to 10 of about 25,431 (290)

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling [PDF]

Frontiers in Pharmacology, 2023
Pharmacogenomics (PGx) studies the impact of interindividual genomic variation on drug response, allowing the opportunity to tailor the dosing regimen for each patient.
Laurentijn Tilleman, Kaat Rubben, Dieter Deforce   +2 more
exaly   +7 more sources

Reliable investigation of DNA methylation using Oxford nanopore technologies [PDF]

Scientific Reports
Oxford Nanopore Technologies (ONT) offers an efficient and effective solution for studying DNA methylation. Both R9.4.1 and R10.4.1 ONT chemistries have been widely used to generate numerous DNA methylation data, making it inevitable to conduct cross-ONT-
Raj Doshi, Evan Kinnear, Sujan Chatterjee, Prasun Guha, Qian Liu   +4 more
doaj   +5 more sources

Assessing the performance of the Oxford Nanopore Technologies MinION

Biomolecular Detection and Quantification, 2015
The Oxford Nanopore Technologies (ONT) MinION is a new sequencing technology that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA molecules presented to it. The device has a low capital cost, is by far the most
Thomas W Laver, David J Studholme
exaly   +6 more sources

Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis [PDF]

Nature Communications, 2021
Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin, Botond Sipos, Phillip L. James, Paul Medvedev   +3 more
doaj   +5 more sources

Oxford Nanopore sequencing: new opportunities for plant genomics?

Journal of Experimental Botany, 2020
DNA sequencing was dominated by Sanger’s chain-termination method until the mid-2000s, when it was progressively supplanted by new sequencing technologies that can generate much larger quantities of data in a shorter time.
Harmeet Singh Chawla, Rod J Snowdon, Björn Usadel   +2 more
exaly   +2 more sources

Oxford Nanopore MinION Sequencing and Genome Assembly

Genomics, Proteomics and Bioinformatics, 2016
The revolution of genome sequencing is continuing after the successful second-generation sequencing (SGS) technology. The third-generation sequencing (TGS) technology, led by Pacific Biosciences (PacBio), is progressing rapidly, moving from a technology ...
Hengyun Lu, Francesca Giordano, Zemin Ning   +2 more
exaly   +2 more sources

Pasteurella multocida genome assembly of Indonesian local isolates using long-read Oxford Nanopore Technology sequencing

Open Veterinary Journal
Background: Pasteurella multocida is a Gram-negative bacterium responsible for various diseases in animals, including Haemorrhagic Septicaemia (HS). Oxford Nanopore Technologies' platform streams sequencing data immediately, allowing for on-the-fly
Sri Suryatmiati Prihandani, I. Wayan Teguh Wibawan, Susan Maphilindawati Noor, Safika Safika, Aswin Rafif Khairullah, Susanti Susanti, Sutiastuti Wahyuwardani, Andriani Andriani, Sumarningsih Sumarningsih, Heri Kurnianto, Tati Ariyanti, Yudi Adinata, Harimurti Nuradji, Alif Rahman Rohim Puarada   +13 more
doaj   +2 more sources

NanoForms: an integrated server for processing, analysis and assembly of raw sequencing data of microbial genomes, from Oxford Nanopore technology [PDF]

PeerJ, 2022
Background Next Generation Sequencing (NGS) techniques dominate today’s landscape of genetics and genomics research. Though Illumina still dominates worldwide sequencing, Oxford Nanopore is one of the leading technologies currently being used by ...
Anna Czmil, Michal Wronski, Sylwester Czmil, Marta Sochacka-Pietal, Michal Cmil, Jan Gawor, Tomasz Wołkowicz, Dariusz Plewczynski, Dominik Strzalka, Michal Pietal   +9 more
doaj   +2 more sources

Rapid Diagnosis of Mycobacterium marinum Infection by Next-Generation Sequencing: A Case Report

Frontiers in Medicine, 2022
We present the first report of histology- and culture-proven Mycobacterium marinum infection diagnosed by next-generation sequencing (NGS). It took <2 days to make a microbiological diagnosis using the Oxford Nanopore Technologies' MinION device ...
Fanfan Xing, Simon K. F. Lo, Yuanchao Ma, Jonathan Daniel Ip, Wan-Mui Chan, Meixun Zhou, Miaozi Gong, Susanna K. P. Lau, Patrick C. Y. Woo   +8 more
doaj   +1 more source

Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection

Genome Biology, 2021
We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu, Lauren Y. Cheng, Ping Song, Sherry X. Chen, Mitesh J. Borad, Lawrence Kwong, Phillip James, Daniel J. Turner, David Yu Zhang   +8 more
doaj   +1 more source