Results 31 to 40 of about 11,306,965 (261)

Amplicon sequencing with Oxford nanopore technologies as a diagnostic alternative for small ruminant lentiviruses in sheep. [PDF]

open access: yesSci Rep
Abstract In Europe, Maedi-Visna disease has high prevalence rates at the individual and flock levels, respectively, and is regarded as one of the most significant infectious disease in sheep. The lack of treatment or a commercial vaccine underscores the need for accurate and reliable diagnostic tools to support ...
Serrano M   +7 more
europepmc   +4 more sources

Benchmarking Oxford Nanopore read alignment‐based insertion and deletion detection in crop plant genomes

open access: yesThe Plant Genome, 2023
Structural variations (SVs) are larger polymorphisms (> 50 bp in length), which consist of insertions, deletions, inversions, duplications, and translocations.
Gözde Yildiz   +5 more
doaj   +1 more source

Oxford Nanopore Technologies sequencing analysis pipeline.

open access: yes, 2021
Flowchart shows each step taken to generate recombinant sequences from Oxford Nanopore sequencing data. Boxes represent processes in the pipeline, diamonds represent decision points and ovals represent termination points. (TIF)
David J. Evans (208308)   +5 more
core   +1 more source

Identification of an emerging cucumber virus in Taiwan using Oxford nanopore sequencing technology

open access: yesPlant Methods, 2022
Abstract Background In June 2020, severe symptoms of leaf mosaic and fruit malformation were observed on greenhouse-grown cucumber plants in Xizhou Township of Changhua County, Taiwan. An unknown virus, designated CX-2, was isolated from a diseased cucumber sample by single lesion isolation on Chenopodium quinoa leaves ...
Zi-Xuan Dong   +4 more
openaire   +3 more sources

Accurate profiling of forensic autosomal STRs using the Oxford Nanopore Technologies MinION device [PDF]

open access: yesForensic Science International: Genetics, 2021
Abstract The high variability characteristic of short tandem repeat (STR) markers is harnessed for human identification in forensic genetic analyses. Despite the power and reliability of current typing techniques, sequence-level information both within and around STRs are masked in the length-based profiles generated.
Courtney L. Hall   +5 more
openaire   +3 more sources

An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations

open access: yesMicromachines, 2023
There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
doaj   +1 more source

Constructing a Reference Genome in a Single Lab: The Possibility to Use Oxford Nanopore Technology [PDF]

open access: yesPlants, 2019
The whole genome sequencing (WGS) has become a crucial tool in understanding genome structure and genetic variation. The MinION sequencing of Oxford Nanopore Technologies (ONT) is an excellent approach for performing WGS and it has advantages in comparison with other Next-Generation Sequencing (NGS): It is relatively inexpensive, portable, has simple ...
Yun Gyeong Lee   +5 more
openaire   +3 more sources

Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly

open access: yesNature Communications, 2016
Pore-forming toxins act by forming oligomeric pores in lipid membranes. Here the authors report the crystal structure of the lysenin pore, providing insights into the assembly and function of the pore in addition to suggesting that its properties make ...
Marjetka Podobnik   +18 more
doaj   +1 more source

Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome

open access: yesGenome Medicine, 2019
Background Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation.
Claudia M. B. Carvalho   +21 more
doaj   +1 more source

Long-read sequencing report with Oxford Nanopore Technologies of different soil samples using different DNA extraction methods.

open access: yes, 2023
Long-read sequencing report with Oxford Nanopore Technologies of different soil samples using different DNA extraction ...
Andrey Zamyatnin (16857811)   +4 more
core   +1 more source

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