Results 61 to 70 of about 463,626 (303)

Insight into biases and sequencing errors for amplicon sequencing with the Illumina MiSeq platform [PDF]

Nucleic Acids Research, 2015
With read lengths of currently up to 2 × 300 bp, high throughput and low sequencing costs Illumina's MiSeq is becoming one of the most utilized sequencing platforms worldwide. The platform is manageable and affordable even for smaller labs. This enables quick turnaround on a broad range of applications such as targeted gene sequencing, metagenomics ...
Schirmer, Melanie, Ijaz, Umer Z., D'Amore, Rosalinda, Hall, Neil, Sloan, William T., Quince, Christopher   +5 more
openaire   +4 more sources

Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk

BMC Medical Genomics
The abundance of Lp(a) protein holds significant implications for the risk of cardiovascular disease (CVD), which is directly impacted by the copy number (CN) of KIV-2, a 5.5 kbp sub-region.
Sairam Behera, Jonathan R. Belyeu, Xiao Chen, Luis F. Paulin, Ngoc Quynh H. Nguyen, Emma Newman, Medhat Mahmoud, Vipin K. Menon, Qibin Qi, Parag Joshi, Santica Marcovina, Massimiliano Rossi, Eric Roller, James Han, Vitor Onuchic, Christy L. Avery, Christie M. Ballantyne, Carlos J. Rodriguez, Robert C. Kaplan, Donna M. Muzny, Ginger A. Metcalf, Richard A. Gibbs, Bing Yu, Eric Boerwinkle, Michael A. Eberle, Fritz J. Sedlazeck   +25 more
doaj   +1 more source

A chromosome-level genome assembly of the jade perch (Scortum barcoo)

Scientific Data, 2022
Measurement(s) whole genome sequencing Technology Type(s) Illumina Sequencing • Oxford Nanopore ...
Yishan Lu, Ruihan Li, Liqun Xia, Jun Cheng, Hongli Xia, Qiuyao Zhan, Dapeng Yu, Xinxin You, Ruobo Gu, Junmin Xu, Qiong Shi, Chao Bian   +11 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Sequence statistics of the Illumina sequencing assembly. [PDF]

, 2012
Sequence statistics of the Illumina sequencing assembly.
Bin Yang (103252), Jia-Ying Zhu (103236), Ning Zhao (84707)   +2 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A Comparison of Base-calling Algorithms for Illumina Sequencing Technology [PDF]

Briefings in Bioinformatics, 2015
Recent advances in next-generation sequencing technology have yielded increasing cost-effectiveness and higher throughput produced per run, in turn, greatly influencing the analysis of DNA sequences. Among the various sequencing technologies, Illumina is by far the most widely used platform.
Ashley Cacho, Ekaterina Smirnova, Snehalata V. Huzurbazar, Xinping Cui   +3 more
openaire   +2 more sources

Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing [PDF]

, 2020
The libraries generated by high-throughput single cell RNA-sequencing (scRNA-seq) platforms such as the Chromium from 10x Genomics require considerable amounts of sequencing, typically due to the large number of cells.
Senabouth, A (15675581), Pebay, A (15628247), Shi, Q (15755174), Beckhouse, A (15755180), Kristof Wing (14753113), Fink, L (15755177), Daniszewski, M (15633953), Shi, L (15615614), Hung, SSC (15629483), Alexander Hewitt (14739028), Jiang, F (15622742), Andersen, S (15709130), Lukowski, SW (15675587), Powell, JE (15633947), Zhang, W (15524786)   +14 more
core  

Sequence statistics of the Illumina sequencing assembly. [PDF]

, 2016
Sequence statistics of the Illumina sequencing assembly.
Songqing Wu (2184277), Yueting Xiong (2184271), Yajie Guo (518157), Yani Mou (2184280), Shuangquan Zou (2184268), Xiong Guan (423435), Feiping Zhang (2184259), Runxue Xu (2184262), Xiaoli Zhu (767993), Zhaoxia Liu (2184283), Ensi Shao (2184274), Guanghong Liang (2184286), Xia Hu (767914), Carballar-Lejarazú Rebeca (2184265)   +13 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source