Results 161 to 170 of about 70,141 (253)

Evaluation of In-room Volumetric Imaging Doses for Image-guided Radiotherapy: A Multi-institutional Study. [PDF]

J Med Phys, 2023
Sakai Y, Monzen H, Takei Y, Kosaka H, Nakamura K, Yanagi Y, Wakabayashi K, Hosono M, Nishimura Y.   +8 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Investigation of the impact of image-guided radiotherapy selection on image registration results and non-coding RNAs for cervical cancer patients. [PDF]

Noncoding RNA Res
Cheng C, Yang Y, Qu Y.
europepmc   +1 more source

Image-guided radiotherapy in an orthotopic mouse model of rectal cancer. [PDF]

STAR Protoc, 2022
Nicolas AM, Pesic M, Rödel F, Fokas E, Greten FR.   +4 more
europepmc   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Performance evaluation of a second-generation O-ring-shaped image-guided radiotherapy system with a gimbal-mounted linear accelerator and real-time tracking capabilities. [PDF]

J Appl Clin Med Phys
Kawata K, Kishigami Y, Hirashima H, Sawada Y, Urago M, Fujimoto T, Fukuda T, Mizowaki T, Nakamura M.   +8 more
europepmc   +1 more source

A small footprint couch-top support device for image-guided radiotherapy of heavy patients. [PDF]

J Appl Clin Med Phys, 2022
Chen H, Morley K, Rodriguez R, Draeger E, Shafiq Ul Hassan M, Chen ZJ.   +5 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Margins of Planning Target Volume and Set-up Errors based on Megavoltage Cone-Beam CT Image Guided Radiotherapy with Helical Tomotherapy: Importance of Automatic Registration Plus Manual Registration. [PDF]

J Biomed Phys Eng
Seifi Makrani D, Banaee N, Geraily G, Nedaie HA, Khorrami Moghaddam A, Jassim HH.   +5 more
europepmc   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source