Results 151 to 160 of about 70,187 (299)

A liquid immunogenic fiducial eluter for image-guided radiotherapy. [PDF]

Front Oncol, 2022
Moreau M, Richards G, Yasmin-Karim S, Narang A, Deville C, Ngwa W.   +5 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Patient doses in image-guided radiotherapy: status in Europe for cone-beam CT imaging in the pelvic region. [PDF]

Radiol Oncol
Kansanoja T, Brovchuk S, Vezirovic M, Petrovic B, Amico AG, Sapignoli S, Paiusco M, Ferrari P, Sá AC, Dias AG, Teles P, Siiskonen T.   +11 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Imaging dose in image-guided radiotherapy for localized prostate intensity-modulated radiotherapy: a nationwide survey in Japan. [PDF]

J Radiat Res
Kito S, Takizawa T, Tanabe S, Suda Y, Nagahata T, Tohyama N, Okamoto H, Kodama T, Fujita Y, Miyashita H, Shinoda K, Kurooka M, Shimizu H, Ohno T, Sakamoto M.   +14 more
europepmc   +1 more source

Risk Factors for Nodal Failure in Patients with FIGO IIIC Cervical Cancer Receiving Definitive Image-Guided Radiotherapy. [PDF]

Curr Oncol, 2023
Liu X, Hou X, Hu K, Zhang F, Wang W, Ren K.   +5 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Radiation therapist (RTT) perspectives on developing image-guided radiotherapy (IGRT) protocols for reirradiation. [PDF]

Tech Innov Patient Support Radiat Oncol
Duffton A, Devlin L, Williamson A, Grose D, Tolmie E, MacLaren L, McFadden S, Muirhead R.   +7 more
europepmc   +1 more source

Electron stream effect in 0.35 Tesla magnetic resonance image guided radiotherapy for breast cancer. [PDF]

Front Oncol, 2023
Lee HH, Wang CY, Chen ST, Lu TY, Chiang CH, Huang MY, Huang CJ.   +6 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source