Results 101 to 110 of about 1,186,551 (242)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Remote Sensing, 2019 Urban remote sensing with moving carriers enables comprehensive monitoring of an urban area. High spatial resolution and wide covering are always required to improve the performance and efficiency of remote sensing.
Dapeng Tian +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Sequential SAR-to-Optical Image Translation
Remote SensingThere is a common need for optical sequence images with high spatiotemporal resolution. As a solution, Synthetic Aperture Radar (SAR)-to-optical translation tends to bring high temporal continuity of optical images and low interpretation difficulty of ...
Jingbo Wei +4 more
doaj +1 more source
Spatial-Intensity Transforms for Medical Image-to-Image Translation. [PDF]
IEEE Trans Med Imaging, 2023 Wang CJ, Rost NS, Golland P.
europepmc +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Bridging the Camera Domain Gap With Image-to-Image Translation Improves Glaucoma Diagnosis. [PDF]
Transl Vis Sci Technol, 2023 He S +9 more
europepmc +1 more source
Image-to-Image Translation with Text Guidance
, 2020 The goal of this paper is to embed controllable factors, i.e., natural language descriptions, into image-to-image translation with generative adversarial networks, which allows text descriptions to determine the visual attributes of synthetic images.
Li, Bowen +3 more
openaire +2 more sources