Results 231 to 240 of about 309,496 (294)

Authors' response to letter to the editor on "image cytometry protocols". [PDF]

J Histochem Cytochem, 2013
Garrido R, Zabka TS, Tao J, Fielden MR, Fretland AJ, Albassam M.   +5 more
europepmc   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry. [PDF]

PLoS One, 2015
Somanchi SS, McCulley KJ, Somanchi A, Chan LL, Lee DA.   +4 more
europepmc   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

High-throughput label-free image cytometry and image-based classification of live Euglena gracilis. [PDF]

Biomed Opt Express, 2016
Lei C, Ito T, Ugawa M, Nozawa T, Iwata O, Maki M, Okada G, Kobayashi H, Sun X, Tiamsak P, Tsumura N, Suzuki K, Di Carlo D, Ozeki Y, Goda K.   +14 more
europepmc   +1 more source

The Distribution of Complement Proteins in Soft and Hard Coronas Impacts Macrophage Uptake of Nanoparticles

Advanced Healthcare Materials, EarlyView.
Protein corona plays a critical role in the biological behavior of nanoparticles. This study investigates the distribution of complement proteins in soft corona and their impact on the macrophage uptake of polymer nanoparticles. It underlines the significance of soft corona investigation for understanding in vivo performance of nanomedicines.
Ying Qiu, Tianchang He, Chunjie Miao, Xinyang Shi, Yuanyuan Niu, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Accurate label-free 3-part leukocyte recognition with single cell lens-free imaging flow cytometry

, 2018
Yuqian Li, Bruno Cornelis, Alexandra Dusa, Geert Vanmeerbeeck, Dries Vercruysse, Erik Sohn, Kamil Blaszkiewicz, Dimiter Prodanov, Peter Schelkens, Liesbet Lagae   +9 more
openalex   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source