Results 231 to 240 of about 285,255 (319)

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back, Moonkyoung Jeong, Huyen‐Thao Le, Ji‐Ho Park   +3 more
wiley   +1 more source

Measurement of monocyte‐platelet aggregates by imaging flow cytometry [PDF]

, 2014
Henry Hui, Kathryn A. Fuller, Wendy N. Erber, Matthew D. Linden   +3 more
openalex   +1 more source

CMOS based image cytometry for detection of phytoplankton in ballast water. [PDF]

Biomed Opt Express, 2017
Pérez JM, Jofre M, Martínez P, Yáñez MA, Catalan V, Parker A, Veldhuis M, Pruneri V.   +7 more
europepmc   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Cutting-Edge Analysis of Extracellular Microparticles using ImageStreamX Imaging Flow Cytometry [PDF]

, 2014
Sarah E. Headland, Hefin R. Jones, Adelina S. V. D'Sa, Mauro Perretti, Lucy V. Norling   +4 more
openalex   +1 more source

Statistical performance of image cytometry for DNA, lipids, cytokeratin, & CD45 in a model system for circulation tumor cell detection. [PDF]

Cytometry A, 2017
Futia GL, Schlaepfer IR, Qamar L, Behbakht K, Gibson EA.   +4 more
europepmc   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Quantum Dot Labelling of Adenovirus Allows Highly Sensitive Single Cell Flow and Imaging Cytometry [PDF]

, 2014
Morgan R. Herod, Robert G. Pineda, Vivien Mautner, David Onion   +3 more
openalex   +1 more source

Authors' response to letter to the editor on "image cytometry protocols". [PDF]

J Histochem Cytochem, 2013
Garrido R, Zabka TS, Tao J, Fielden MR, Fretland AJ, Albassam M.   +5 more
europepmc   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source