Results 81 to 90 of about 285,255 (319)
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Cancer Informatics, 2008 Background: Nuclear grade has been associated with breast DCIS recurrence and progression to invasive carcinoma; however, our previous study of a cohort of patients with breast DCIS did not find such an association with outcome. Fifty percent of patients
Judith-Anne W. Chapman +7 more
doaj
Machine‐Learning‐Assisted Intelligent Imaging Flow Cytometry: A Review
Advanced Intelligent Systems, 2021 Imaging flow cytometry has been widely adopted in numerous applications such as optical sensing, environmental monitoring, clinical diagnostics, and precision agriculture.
Shaobo Luo +9 more
doaj +1 more source
Image Analysis Cytometry of Dysplastic Nevi
Journal of Investigative Dermatology, 1990 Computerized image analysis was used to assess nuclear atypia in 24 dysplastic nevi (DN), 19 CN (CN), and five thin melanomas. DN were selected for the study using architectural criteria alone. Feulgen-stained, 6-um sections were analyzed with a microTICAS cytometer. At least 100 nuclei were measured in each case. The standard deviation of nuclear area,
Matthew G Fleming +5 more
openaire +3 more sources
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. [PDF]
, 2019 Ovarian cancer and triple-negative breast cancer are among the most lethal diseases affecting women, with few targeted therapies and high rates of metastasis. Cancer cells are capable of evading clearance by macrophages through the overexpression of anti-
Barkal, Amira A +10 more
core
Lensless wide-field fluorescent imaging on a chip using compressive decoding of sparse objects. [PDF]
, 2010 We demonstrate the use of a compressive sampling algorithm for on-chip fluorescent imaging of sparse objects over an ultra-large field-of-view (>8 cm(2)) without the need for any lenses or mechanical scanning.
Coskun, Ahmet F +3 more
core +2 more sources
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Additional Techniques in Serous Effusions
Analytical Cellular Pathology, 2002 Cytological examination is a valuable diagnostic tool in case of a serous effusion. The firstmanifestation of malignancy may be an effusion of the pleural, pericardial, or peritoneal cavity, especially in carcinoma of the ovary, or lung, and malignant ...
A. G. J. M. Hanselaar
doaj +1 more source
Multiparametric Image Cytometry in Mycosis Fungoides
Journal of Investigative Dermatology, 1996 Eighteen cases of early mycosis fungoides were compared with 18 cases of eczematous dermatitis by multiparametric image cytometry. A minimum of 100 lymphocytes was measured in each case. A large number of measurements was acquired for each lymphocyte, characterizing nuclear DNA content, area, shape, and texture.
Thomas W. Rauber, Matthew G. Fleming
openaire +3 more sources