The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Dis/re-orienting design through norm-critical gender lenses: an educational case in Turkey
Design, as a practice of developing solutions beyond products, and increasingly services and policies, inevitably poses an impact on gender (in)equality which remains largely unrecognized by design practitioners.
Erman Örsan Yetiş +2 more
doaj +1 more source
Practised imagination : tracing transnational networks in Crete and beyond ; paper for the conference 'Alltag der Globalisierung. Perspektiven einer transnationalen Anthropologie', January 16-18, 2003, Institute of Cultural Anthropology and European Ethnology, Johann Wolfgang Goethe University, Frankfurt am Main [PDF]
The imagination has become a major site for studying transnational cultural flows. Yet it is mainly the mass media that are explored as channels directing the imagination from "the West" towards "the rest".
Römhild, Regina
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Relationship between Imagination and Knowledge in MullaSadra’s Philosophy [PDF]
In this study, we try to show a pattern of philosophical view of Mulla Sadra about the relationship between imagination and knowledge based on an analytic methodology.
sayed mahdi mirhadi +2 more
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Early Modern Persian, Urdu, and English Historiography and the Imagination of Islamic India under British Rule [PDF]
Blain Auer
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Faculty Essay: On Civility [PDF]
Our collective imagination is presently being held captive by a politics of name-calling, bullying and fear-mongering.
Buccola, Nicholas
core +1 more source

