Results 51 to 60 of about 706,588 (183)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Influence of Connecting Two Standalone Mobile Three-Dimensional Scanners on Accuracy Comparing with a Standard Device in Facial Scanning

eJournal of Oral Maxillofacial Research, 2017
Objectives: In this study is investigated if bundling of two scanners leads to better accuracy in recording faces than a standard face-scanning device. Material and Methods: In a group of 28 volunteers, two test specimens were attached to their faces:
Ali Modabber, Florian Peters, Anna Brokmeier, Evgeny Goloborodko, Anna Brokmeier, Alireza Ghassemi, Bernd Lethaus, Frank Hölzle, Stephan Christian Möhlhenrich, Frank Hölzle   +9 more
doaj   +1 more source

Proton magnetic resonance imaging with a nitrogen-vacancy spin sensor

, 2014
Nuclear magnetic resonance (NMR) imaging with nanometer resolution requires new detection techniques with sensitivity well beyond the capability of conventional inductive detection.
Awschalom, D. D., Kim, M., Mamin, H. J., Ohno, K., Rettner, C. T., Rugar, D., Sherwood, M. H.   +6 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Progress in Three-Dimensional Coherent X-Ray Diffraction Imaging [PDF]

, 2005
The Fourier inversion of phased coherent diffraction patterns offers images without the resolution and depth-of-focus limitations of lens-based tomographic systems.
Barty, A., Beetz, T., Chapman, H. N., Cui, C., Hau-Riege, S. P., He, H., Howells, M. R., Jacobsen, C., Kinney, J. M., Lima, E., Marchesini, S., Minor, A. M., Noy, A., Rosen, R., Shapiro, D., Spence, J. C. H., Weierstall, U.   +16 more
core   +1 more source

Three Dimensional Annihilation Imaging of Antiprotons in a Penning Trap

, 2003
We demonstrate three-dimensional annihilation imaging of antiprotons trapped in a Penning trap. Exploiting unusual feature of antiparticles, we investigate a previously unexplored regime in particle transport; the proximity of the trap wall.
Amoretti, M., Bonomi, G., Bouchta, A., Bowe, P. D., Carraro, C., Cesar, C. L., Charlton, M., Doser, M., Filippini, V., Fontana, A., Fujiwara, M. C., Funakoshi, R., Genova, P., Hangst, J. S., Hayano, R. S., Jorgensen, L. V., Lagomarsino, V., Landuad, R., Lindelof, D., Macri, M., Madsen, N., Marchesotti, M., Montagna, P., Pruys, H., Regenfus, C., Rielder, P., Rizzini, E. Lodi, Rotondi, A., Testera, G., van der Werf, D. P., Variola, A.   +30 more
core   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

From Frictional to Viscous Behavior: Three Dimensional Imaging and Rheology of Gravitational Suspensions [PDF]

, 2010
We probe the three dimensional flow structure and rheology of gravitational (non-density matched) suspensions for a range of driving rates in a split-bottom geometry. We establish that for sufficiently slow flows, the suspension flows as if it were a dry
C. Ancey, Christian R. Berardi, Elie Wandersman, Joshua A. Dijksman, Martin van Hecke, Steven Slotterback, William Derek Updegraff, Wolfgang Losert   +7 more
core   +5 more sources

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source