Results 51 to 60 of about 1,882,249 (253)

Physical Anthropomorphic Breast Phantoms for X-ray Imaging Techniques: Manufacturing Approach

, 2020
Anthropomorphic physical phantoms in radiology permit unlimited exposure. In breast imaging, they are used to validate, evaluate and optimise novel imaging techniques for screening and diagnosis, as well as for systems’ quality control.
Bliznakova K., Okkalidis N., Bliznakov Z., Mettivier G., Russo P., Dukov N., Sarno A., Nikiforos Okkalidis, Nikolay Dukov, Paolo Russo, Kristina Bliznakova, Antonio Sarno, Giovanni Mettivier, Zhivko Bliznakov   +13 more
core   +1 more source

Optical Tissue Phantoms for Quantitative Evaluation of Surgical Imaging Devices

, 2022
Optical tissue phantoms (OTPs) have been extensively applied to the evaluation of imaging systems and surgical training. Due to their human tissue‐mimicking characteristics, OTPs can provide accurate optical feedback on the performance of image‐guided ...
Homan Kang, Sylvain Gioux, Jason Dinh, Hak Soo Choi, Atsushi Yamashita, Kang, H. (Homan), Dinh, Jason, Gioux, S. (Sylvain), Choi, H. (Hak Soo), Choi, Hak, Soo, Dinh, J. (Jason), Gioux, Sylvain, Yamashita, Atsushi, Kang, Homan, Yamashita, A. (Atsushi)   +14 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Advancing Phantom Fabrication: Exploring 3D-Printed Solutions for Abdominal Imaging Research

Applied Sciences
Background: The development of novel medical imaging technologies and treatment procedures hinges on the availability of accurate and versatile phantoms.
Muris Becircic, Samir Delibegovic, Adnan Sehic, Fuad Julardzija, Adnan Beganovic, Kenana Ljuca, Adi Pandzic, Merim Jusufbegovic   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Tissue-like phantoms for quantitative birefringence imaging

, 2017
Birefringence imaging, including polarization sensitive optical coherence tomography (PS-OCT), can provide valuable insight into the microscopic structure and organization of many biological tissues.
Liu, Linbo, Brett E. Bouma, Liu, L. B., Martin Villiger, Kathy Beaudette, Bouma, B. E., Liu, X. Y., Wang, X. H., Liu, Xinyu, Xianghong Wang, Villiger, M., Linbo Liu, Xinyu Liu, Villiger, Martin, Beaudette, Kathy, Wang, Xianghong, Bouma, Brett E.   +16 more
core   +1 more source

Mechanically Powered Motion Imaging Phantoms: Proof of Concept [PDF]

, 2019
Motion imaging phantoms are expensive, bulky and difficult to transport and set-up. The purpose of this paper is to demonstrate a simple approach to the design of multi-modality motion imaging phantoms that use mechanically stored energy to produce ...
Toussaint, N, Toussaint, Nicolas,, Schmitz, Cornelia,, Schnabel, J, Schnabel, Julia A.,, Henningsson, Markus,, Zimmer, Veronika A.,, Oksuz, I, Housden, JR, Gomez, Alberto,, Schmitz, Cornelia, Toussaint, Nicolas, Clough, James R.; id_orcid, Schnabel, Julia A.; id_orcid, Noh, Yohan, King, Andrew P.; id_orcid, King, A, Zimmer, Veronika A., Clough, James R.,, Henningsson, M, Noh, Yohan,, Zimmer, V, Housden, James, Oksuz, Ilkay,, Oksuz, Ilkay; id_orcid, Housden, James,, Noh, Y, Clough, J, Schmitz, C, King, Andrew P.,, Gomez, A, Henningsson, Markus, Gomez, Alberto   +32 more
core   +1 more source

Development of Phantoms for Multimodal Magnetic Resonance Imaging and Magnetic Particle Imaging

, 2022
Phantoms are crucial for the development of imaging techniques based on magnetic nanoparticles (MNP). They serve as test objects to simulate application scenarios but are also used for quality assurance and interlaboratory comparisons.
Olaf Kosch, Maria Alejandra Ardila Arenas, Rüdiger Brühl, Löwa, Norbert, Dirk Gutkelch, Norbert Löwa, Brühl, Rüdiger, Kosch, Olaf, Gutkelch, Dirk, Wiekhorst, Frank, Arenas, Maria Alejandra Ardila, Frank Wiekhorst   +11 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source