Results 71 to 80 of about 1,882,249 (253)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Hydrogel based depth standards and phantoms for optical imaging applications

Medical imaging technology is advancing rapidly making disease diagnostics faster, efficient, and detailed. Currently much effort is focused on designing and fabricating new NIR laser sources and detectors, devising novel label free imaging ...
Haseeb, Fizza
core   +1 more source

In Silico Phase-Contrast X-Ray Imaging of Anthropomorphic Voxel-Based Phantoms

, 2021
Propagation-based phase-contrast X-ray imaging is an emerging technique that can improve dose efficiency in clinical imaging. In silico tools are key to understanding the fundamental imaging mechanisms and develop new applications.
Shaker, Kian, Shaker, Kian,, Hertz, Hans,, Häggmark, Ilian, Häggmark, Ilian,, Hertz, Hans, Kian Shaker, Hans M. Hertz, Ilian Haggmark   +8 more
core   +1 more source

Chemical items used for preparing tissue-mimicking material of wall-less flow phantom for doppler ultrasound imaging

Journal of Medical Ultrasound, 2018
The wall-less flow phantoms with recognized acoustic features (attenuation and speed of sound), interior properties, and dimensions of tissue were prepared, calibrated, and characterized of Doppler ultrasound scanning demands tissue-mimicking materials ...
Ammar A Oglat, M Z Matjafri, Nursakinah Suardi, Mohammad A Oqlat, Mostafa A Abdelrahman, Ahmad A Oqlat, Omar F Farhat, Batool N Alkhateb, Raed Abdalrheem, Muntaser S Ahmad, Mohammed Y. M. Abujazar   +10 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Technical Validation of Photoacoustic Imaging Systems Using Phantoms

Technical validation studies are paramount for objective performance evaluation and calibration of novel imaging devices, aiding their development and effective translation into clinical practice.
Joseph, James; id_orcid, Hacker, Lina
core   +1 more source

Advancements in Retinal Tissue-Mimicking Optical Coherence Tomography Phantoms: Materials, Properties, and Applications

BioChem
Optical coherence tomography (OCT) phantoms are essential tools for calibrating imaging systems, validating diagnostic algorithms, and bridging technological advancements with clinical applications. This review explores the development and application of
Mukhit Kulmaganbetov
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Development and application of a set of mesh-based and age-dependent Chinese family phantoms for radiation protection dosimetry: Preliminary Data for external photon beams

EPJ Web of Conferences, 2017
A group of mesh-based and age-dependent family phantoms for Chinese populations were developed in this study. We implemented a method for deforming original RPI-AM and RPI-AF models into phantoms of different ages: 5, 10 ,15 and adult.
Pi Yifei, Zhang Lian, Huo Wanli, Feng Mang, Chen Zhi, Xu X. George   +5 more
doaj   +1 more source