Results 51 to 60 of about 81,920,088 (158)
Medicinal Insights Into FLT3 Inhibitors as Anticancer Agents: Current Status and Future Direction
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.Structure–activity relationship of FMS‐like tyrosine kinase 3 (FLT3) as potent anti‐cancer agents supported by biological evaluation, in silico and clinical trial studies. ABSTRACT FMS‐like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase (RTK) important for hematopoietic stem cell proliferation, differentiation, and survival.
Ankush Kumar +4 more
wiley +1 more source
2-Aryl-3-Vinyl Substituted Imidazo[1,2-a]pyridines and fluorescent electrocyclization derivatives therefrom [PDF]
, 2020 A collection of 2-aryl-3-vinylimidazo[1,2-a]pyridines, substituted on the pyridine ring and/or the aryl substituent, can be obtained by reaction of 2-aminopyridines with properly substituted nitrobutadienes, originated by an initial ring opening of a ...
Tavani C. +5 more
core +1 more source
Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley +1 more source
Mild and Metal‐Free CH Arylation of Imidazoles via In Situ Diazotization in Water
Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.Imidazoles undergo direct C–H arylation through in situ generated diazonium salts in water, under ambient and catalyst‐free conditions. This operationally simple method avoids hazardous intermediates, tolerates sensitive functional groups, and preserves C–halogen bonds.
Elisabetta Rosadoni +3 more
wiley +1 more source
Transition-metal-free synthesis of triarylmethanes via Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives [PDF]
A facile, transition-metal-free, HFIP-promoted method for the synthesis of triarylmethanes through direct Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives has been described, which allows for efficient synthesis of ...
Kai Yang +4 more
core +1 more source
In‐situ‐Konstruktion von Imidazopyridinium‐Fluoreszenzlabels für Biokonjugationen
Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.Durch Chromophor‐Engineering von Isochinolinaldehyden entstehen TICT‐basierte fluorogene Farbstoffe für die In Situ Markierung unterschiedlicher (Bio‐)Moleküle mit großen Stokes‐Verschiebungen, die mit der Zellbildgebung kompatibel sind. ZUSAMMENFASSUNG Einfache, effiziente Transformationen fluorogenen Charakters, die unter biokompatiblen Bedingungen ...
Dongchen Du +7 more
wiley +1 more source
Synthesis of imidazo 1,2-a pyridines from unactivated 2-alkyl-4,5-dihydroimidazoles through conjugate N-addition [PDF]
, 2000 2-Alkyl-4,5-dihydroimidazoles undergo annulation with alpha,beta-unsaturated aldehydes and ketones via conjugate addition of the N-1 nitrogen atom and subsequent enamine-aldol condensation of C(alpha) to form imidazo[1,2-a]pyridines having reversed ...
Light, M.E. +4 more
core
In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation
Angewandte Chemie International Edition, Volume 65, Issue 21, 18 May 2026.Chromophore engineering of isoquinoline aldehydes generates TICT‐based fluorogenic dyes for in situ labeling of diverse (bio)molecules with large Stokes shifts compatible with cell imaging. ABSTRACT Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts are of high ...
Dongchen Du +7 more
wiley +1 more source
ChemCatChem, Volume 18, Issue 9, 14 May 2026.Group 6 metal complexes of Cr, Mo, and W supported by N‐heterocyclic carbenes are emerging as versatile platforms for homogeneous catalysis. This review highlights advances in reduction, hydrogen transfer, oxidation, and small molecule activation, revealing how ligand design controls reactivity and opens sustainable alternatives to noble‐metal ...
Beatriz Garcia +2 more
wiley +1 more source
Heterocyclization of Functionalized Vinylic Derivatives of Imidazo[1,2-a]pyridines [PDF]
, 2016 Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-a]pyridines was explored experimentally and theoretically using semiempirical AM1 and ab initio methods.
Jean M. Chezal (3030081) +8 more
core +3 more sources