A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon +1 more
wiley +1 more source
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández +6 more
core +1 more source
Pseudomonas aeruginosa causes many infections worldwide. Multidrug-resistant bacteria are mostly watched in hospital-acquired infections and are linked with high mortality rates. This study aims to find a possible cure for P.
Siddiqui Fatima +7 more
doaj +1 more source
Prevalence of ESBL in Escherichia coli Isolates Among ICU Patients in a Tertiary Care Hospital [PDF]
Introduction: Resistance to common antibiotics is a matter of grave concern in treating infections in hospital settings especially in Intensive Care Units (ICUs).
Nipa Singh +4 more
doaj +1 more source
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi +4 more
wiley +1 more source
Bacillary angiomatosis in HIV-infected patients - An epidemiological and clinical study [PDF]
Background: No data were available on the epidemiological and clinical characteristics of bacillary angiomatosis (BA) in Germany. Objective:To determine epidemiological and clinical data on HIV-associated BA.
Albrecht, H. +9 more
core +1 more source
Antibiotic resistance and molecular typing of Pseudomonas aeruginosa: focus on imipenem
Susceptibility tests by disk diffusion and by E-test and molecular typing by macrorestriction analysis were performed to determine the relatedness of Pseudomonas aeruginosa isolates from three distinct hospitals. The resistance profile of 124 isolates to
Ana Lúcia Peixoto de Freitas +1 more
doaj +1 more source
Imipenem is the most efficient antibiotic against Acinetobacter baumannii infection, but new research has shown that the organism has also developed resistance to this agent. A.
Abdelhamed Mahmoud +4 more
doaj +1 more source
Decision fatigue in hospital medicine: A retrospective exploratory evaluation
Abstract Background “Decision fatigue” (DF) is the deterioration in decision‐making ability stemming from repeated decision making. Objective Explore DF over the clinical workblock and across hospitalist and work characteristics. Methods Patients seen by hospitalists at two hospitals in January and February 2022 were retrospectively evaluated for ...
Rachel M. Kruer +6 more
wiley +1 more source
Distributed lags time series analysis versus linear correlation analysis (Pearson's r) in identifying the relationship between antipseudomonal antibiotic consumption and the susceptibility of Pseudomonas aeruginosa isolates in a single Intensive Care Unit of a tertiary hospital [PDF]
The relationship between antibiotic consumption and selection of resistant strains has been studied mainly by employing conventional statistical methods.
Bielen, Luka +7 more
core +1 more source

