Results 51 to 60 of about 4,823 (126)

Exploring the additive antibacterial potential of Cinnamomum cassia volatile oil and imipenem against Acinetobacter baumannii: a multi-omics investigation

open access: yesFrontiers in Microbiology
IntroductionAcinetobacter baumannii has been identified as a critical pathogen, and new antibiotics are urgently needed. Volatile oils, which function as natural antibacterial agents, may provide an effective means of inhibiting A. baumannii.
Youyuan Lu   +9 more
doaj   +1 more source

The Role of Pharmacovigilance Database in Identifying Antibiotic Resistance and Inappropriate Use: An Analysis of VigiBase Reports From Lower‐Middle‐Income Countries

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Background Digital databases such as pharmacovigilance (PV) databases could provide unique opportunities to monitor trends in suspected antibiotic resistance, ineffectiveness, and misuse, extending beyond their traditional role of tracking adverse drug reactions (ADRs).
Hager Saleh   +3 more
wiley   +1 more source

Clinical characteristics, specific resistance patterns, and molecular mechanisms of carbapenem-resistant Morganella morganii isolates

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectivesThe emergence and spread of carbapenem-resistant Morganella morganii (M. morganii) pose a serious global challenge. This study aimed to investigate the clinical characteristics, resistance patterns, and molecular mechanisms of carbapenem ...
Xiangkuo Zheng   +8 more
doaj   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

open access: yesVIEW, Volume 7, Issue 3, June 2026.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang   +9 more
wiley   +1 more source

Treatment and Follow up of Pseudomonas Endophtalmitis due to Contact Lens Use

open access: yesMedicine Science, 2013
The use of contact lenses is the most common cause of bacterial keratitis. Pseudomonas aurogenoza is the most common factor. We aimed to present diagnosis, treatment and follow up a 21 yeas old female patient with endophtalmitis secondary to multi-drug ...
Tongabay Cumurcu   +2 more
doaj   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

Evaluation the antibacterial activity of nanoantibiotics imipenem and ciprofloxacin loaded in human serum albumin against some antibiotic-resistant pathogenic bacteria

open access: yesJournal of Experimental Nanoscience, 2020
Introduction Microbial resistance is increasing worldwide. Investigations are underway to use nanoparticles as antimicrobial agents to reduce microbial resistance.
Shima Shafiei   +3 more
doaj   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik   +44 more
wiley   +1 more source

Population pharmacokinetics of imipenem in different populations for individualized dosing: a systematic review

open access: yesFrontiers in Pharmacology
BackgroundImipenem is a broad-spectrum carbapenem antibiotic for severe infections with significant pharmacokinetic (PK) variability. This review systematically synthesized published population pharmacokinetic (popPK) studies to identify key covariates ...
Ping Zhang   +7 more
doaj   +1 more source

High Resistance and Biofilm Tolerance to Antimicrobials of Marine Bacteria From Brazilian Deep‐Sea Sediment

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Antimicrobial resistance and biofilm‐specific tolerance of cultivable Pseudomonas, Bacillus, Brevibacillus and Paenibacillus isolated from deep‐sea sediments of a methane‐seep area off the Southern Brazilian coast. These findings underscore the role of deep‐sea environments as potential reservoirs for antimicrobial‐resistant bacteria (ARB) and ...
Amanda Simão Dias   +2 more
wiley   +1 more source

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