Results 61 to 70 of about 4,823 (126)

The expansion of culturable opportunistic pathogens and antibiotic resistance in mouse gut following antibiotic exposure

Microbiology Spectrum
Antibiotics significantly change gut microbiota, leading to dysbiosis and changes in bacterial community composition, which further results in a series of dysfunctions with severe health consequences.
Bianfang Wang, Jian Zhang, Yuqing Sun, Xin Wei, Wenli Lai, Tingting Guo, Chengzhang Fu, Youming Zhang, Hai Xu, Ling Li, Mingyu Wang   +10 more
doaj   +1 more source

Modulation of Quorum Sensing and Virulence Gene Expression in Escherichia coli by Extracts of Physalis alkekengi

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Root extracts of Physalis alkekengi were examined for activity against multidrug‐resistant (MDR) Escherichia coli. The ethanolic extract suppressed bacterial growth, lowered biofilm formation by ~63%, and markedly reduced expression of luxS and fimH. Findings highlight P.
Mansoureh Esfandiyari Doolaby, Mohammad Javad Mehdipour Moghaddam, Akbar Norastehnia   +2 more
wiley   +1 more source

Efficacies of omadacycline + amikacin + imipenem and an all-oral regimen omadacycline + clofazimine + linezolid in a mouse model of M. abscessus lung disease

mSphere
Treatment outcomes for Mycobacteroides abscessus (Mab, also known as Mycobacterium abscessus) disease are still unsatisfactory, mainly due to issues with drug toxicity, tolerability, and efficacy.
Elisa H. Ignatius, Binayak Rimal, Chandra M. Panthi, Daniel C. Belz, Christopher K. Lippincott, Daniel H. Deck, Alisa W. Serio, Gyanu Lamichhane   +7 more
doaj   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Leen Ali, Elie Salem Sokhn, Charbel Khalil, Fatima A. Saleh   +3 more
wiley   +1 more source

Potential Use and Chemical Analysis of Some Natural Plant Extracts for Controlling Listeria spp. Growth In Vitro and in Food

Foods
Listeria are Gram-negative intracellular foodborne pathogens that can cause invasive infections with high mortality rates. In this work, the antibacterial activity of ten essential oils, infusion extracts, and decoction extracts of some medicinal plants ...
Abdul-Raouf Al-Mohammadi, Seham Abdel-Shafi, Ahmed H. Moustafa, Nehal Fouad, Gamal Enan, Rehab A. Ibrahim   +5 more
doaj   +1 more source

CLINICAL AND PHARMACOECONOMIC ANALYSIS OF CARBAPENEMS (MEROPENEM, IMIPENEM AND DORIPENEM) IN NOSOCOMIAL PNEUMONIA TREATMENT

Фармакоэкономика, 2015
the article presents the results of a retrospective study conducted in the period from 2008 to 2011 in Moscow’s hospitals. The aim of the study was to compare the clinical and pharmacoeconomical efficacy of carbapenems in nosocomial pneumonia treatment ...
I. I. Shteynberg, S. K. Zyryanov, Yu. B. Belousov   +2 more
doaj  

Mechanisms of Heteroresistance and Resistance to Imipenem in Pseudomonas aeruginosa

Infection and Drug Resistance, 2020
Ye Xu,1 Xiangkuo Zheng,2 Weiliang Zeng,2 Tao Chen,1 Wenli Liao,1 Jiao Qian,1 Jie Lin,1 Cui Zhou,1 Xuebin Tian,2 Jianming Cao,2 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang ...
Xu Y, Zheng X, Zeng W, Chen T, Liao W, Qian J, Lin J, Zhou C, Tian X, Cao J, Zhou T   +10 more
doaj  

Imipenem Resistance and BLAIMP Gene among Hospital Strains of Pseudomonas aeruginosa at University Hospital in Egypt

Journal of Infection in Developing Countries, 2007
Background: Imipenem (IMP) is considered the last resort for treatment of infections caused by resistant Gram negative bacteria in our setting. However, in recent times, multi-drug resistant strains of P.
Fatma A. Amer,1 Eman M. El-Behedy,1 Heba A. Mohtady,1 Hala E. Zanfaly,2 Dalal E. M. Soud,2 Tarek M. El-Behedy,3 Eman El-Gendy.3
doaj  

Prevalence of on time administration of carbapenem and its impact on PK/PD target attainment in hospitalized patients: a multicenter retrospective study

Frontiers in Cellular and Infection Microbiology
ObjectiveOn time administration of carbapenem is important, but there are few data concerning the prevalence of timeliness and its impact on pharmacokinetic/pharmacodynamic (PK/PD) target achievement in hospitalized patients.MethodsThis was a multicenter
Jin Song, Xiaoping Pang, Huadong Chen, Ping Zhang, Miaofa Ying, Renai Xu, Zhenwei Yu, Zhenwei Yu   +7 more
doaj   +1 more source