Results 91 to 100 of about 19,050 (169)

Regional distribution and elimination kinetics of imipramine in rat brain after a single intraperitoneal administration.

open access: bronze, 1986
Mikio Masada   +7 more
openalex   +2 more sources

A Case of Imipramine(Tofranil®) Poisoning with Cardiac Arrhythmias

open access: hybrid, 1980
Seong‐Hoon Park   +4 more
openalex   +1 more source

Characterization of 3H-imipramine specific binding to the whole cell preparation of blood platelets

open access: gold, 1989
Yuki Jikoh   +4 more
openalex   +1 more source

Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer

open access: yesFrontiers in Oncology, 2021
Background Anti-depressants have been reported to own anti-tumor potential types of cancers; however, the role of imipramine in non-small cell lung cancer (NSCLC) has not been elucidated. Epidermal growth factor receptor (EGFR) was known to be one of the
Yuan-hao Lee   +2 more
exaly   +2 more sources

Imipramine impedes glioma progression by inhibiting YAP as a Hippo pathway independent manner and synergizes with temozolomide

open access: yesJournal of Cellular and Molecular Medicine, 2021
Patients with malignant glioma often suffered from depression, which leads to an increased risk of detrimental outcomes. Imipramine, an FDA‐approved tricyclic antidepressant, has been commonly used to relieve depressive symptoms in the clinic.
Xiuping Zhou, Rutong Yu
exaly   +2 more sources

Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF‐κB signalling participate in anti‐glioblastoma of imipramine

open access: yesJournal of Cellular and Molecular Medicine, 2020
Glioblastomas are the most aggressive type of brain tumour, with poor prognosis even after standard treatment such as surgical resection, temozolomide and radiation therapy. The overexpression of the nuclear factor kappa‐light‐chain‐enhancer of activated
I-tsang Chiang, Fei-ting Hsu
exaly   +2 more sources

New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

open access: yesExperimental and Molecular Medicine, 2020
Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal growth factor receptor (EGFR) and overexpression of fascin1, a key protein in ...
Begoña Alburquerque-gonzález   +2 more
exaly   +2 more sources

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