Results 91 to 100 of about 51,042 (305)

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Experimental Evidence for the Involvement of PDLIM5 in Mood Disorders in Hetero Knockout Mice [PDF]

open access: yes, 2013
BackgroundReports indicate that PDLIM5 is involved in mood disorders. The PDLIM5 (PDZ and LIM domain 5) gene has been genetically associated with mood disorders; it’s expression is upregulated in the postmortem brains of patients with bipolar disorder ...
Arinami Tadao   +8 more
core   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

open access: yesDrug Testing and Analysis, Volume 17, Issue 9, Page 1502-1515, September 2025.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer   +4 more
wiley   +1 more source

Effect of Local and Application of Amitriptyline and Imipramine on Teeth with Irreversible Pulpitis Failed Pulpal Anesthesia: A Randomized, Double-blind, Controlled Trial

open access: yesDental Hypotheses, 2016
Introduction: To evaluate the analgesic effect of amitriptyline and imipramine after local application on the dentine of “hot teeth” with failed pulpal anesthesia.
Mohsen Aminsobhani   +5 more
doaj   +1 more source

Phytochemical and Bioactivity Profiling of Unconventional Food Plant, Boehmeria caudata Leaves: FT‐IR, GC–MS, Experimental, and In Silico Investigation

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
In this paper, we have investigated the in vitro antioxidant as well as in vivo analgesic, anxiolytic, and antidepressant activities of the methanolic extract of Boehmeria caudata leaves, alongside a phytochemical evaluation using FT‐IR and GC‐MS analysis.
Md. Liakot Ali   +9 more
wiley   +1 more source

National Prescribing Trends and Cost Analysis of Antidepressants, Anxiolytics, and Hypnotics in England, 2010–2023

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 40, Issue 5, September 2025.
ABSTRACT Introduction We describe prescribing of anxiolytics/hypnotics/antidepressants at an all‐England level between 2010 and 2023, taking account of the influence of the COVID‐19 pandemic‐period. Methods All Primary Care Prescribing data for England for anxiolytics/hypnotics/antidepressant agents taken as tablets or capsules from 1 January 2010 to ...
Mike Stedman   +5 more
wiley   +1 more source

Comparison between efficacy of imipramine and transcutaneous electrical nerve stimulation in the prophylaxis of chronic tension-type headache: A randomized controlled clinical trial

open access: yesJournal of Research in Medical Sciences, 2011
Background: Chronic tension-type headache (CTTH) is recognized as the most common type of headache and can be further defined as either episodic or chronic.
Sayed Ali Mousavi   +2 more
doaj  

A truly knotless technique for scleral fixation of intraocular lenses: Two-year results

open access: yesIndian Journal of Ophthalmology, 2012
Scleral fixated intraocular lens (SFIOL) is a safe and effective option for managing optical aphakia. Suture related complications like suture erosion, suture breakage, endophthalmitis, etc. are unique to SFIOL.
Naresh K Yadav   +3 more
doaj   +1 more source

Antidepressants in the Management of Chronic Pain Syndromes [PDF]

open access: yes, 1990
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90213/1/j.1875-9114.1990.tb02582.x ...
Chaffee, Betty J., Egbunike, Ifeanyi G.
core   +1 more source

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