Results 91 to 100 of about 49,920 (311)
Repeated administration of imipramine modifies GABAergic transmission in rat frontal cortex [PDF]
Alterations in the functions of brain gamma-aminobutyric acid (GABA) inhibitory system and a distortion in the balance between excitatory and inhibitory synaptic transmission have been hypothesized to be possible causes of mood disorders.
Hess, Grzegorz, Wabno, Joanna
core +1 more source
Opportunities and Challenges of Population Pharmacogenomics
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou+3 more
wiley +1 more source
Background: Chronic tension-type headache (CTTH) is recognized as the most common type of headache and can be further defined as either episodic or chronic.
Sayed Ali Mousavi+2 more
doaj
Trends in tricyclic antidepressant prescribing and poisoning in England and Wales 2016–2020
Abstract Aims Tricyclic antidepressants (TCAs) are commonly prescribed despite no longer being a NICE‐recommended first‐line treatment for depression and their recognized toxicity in overdose. This study examined prescribing, mortality, hospital admissions and clinical TCA data to quantify the use and impact of TCAs in England and Wales.
Laurence Gray+10 more
wiley +1 more source
Depression is a major health problem and is not only underrecognized and undertreated but is associated with significant morbidity and mortality. Lavandula officinalis is used to treat depression.
M Khani+5 more
doaj
Aims & Objectives: To compare the occurrence of hyponatremia in the patients receiving two different Tricyclic Antidepressants (TCAs)–Amitriptyline and Imipramine Methodology: Fifty OPD patients attendingthe Psychiatry outpatient clinic of Mahatma Gandhi
Seema Singh Parmar, P B Behere
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α2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment [PDF]
Slow-onset adaptive changes that arise from sustained antidepressant treatment, such as enhanced adult hippocampal neurogenesis and increased trophic factor expression, play a key role in the behavioral effects of antidepressants.
Bartlett, Perry+12 more
core +1 more source
Combination therapy with antidepressants and sleep medications is a promising candidate treatment for major depressive disorder (MDD) with insomnia. This systematic review and meta‐analysis examined the efficacy and safety of combination therapy with antidepressants and sleep medication for treating MDD with insomnia compared to antidepressant ...
Taku Maruki+9 more
wiley +1 more source
Thomson T Tai,1,2 Brent T Tai,2,3 Yu-Jun Chang,2 Kuo-Hsuan Huang4,5 1Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA; 2Department of Epidemiology and Biostatistics, Changhua Christian Hospital, Changhua, Taiwan; 3Burrell College ...
Tai TT, Tai BT, Chang YJ, Huang KH
doaj