Results 71 to 80 of about 38,471 (252)

Role of Pain in Adults Undergoing Soft Tissue and Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.
ABSTRACT Objective In adult patients who undergo soft tissue and maxillomandibular advancement (MMA) sleep surgery for obstructive sleep apnea (OSA), we identify preoperative pain diagnoses and postoperative pain medication dispensing patterns by surgery type.
Ghedak Ansari, Jeanne A. Darbinian, Samuel A. Collazo, Nikolas R. Block‐Wheeler, Megan L. Durr   +4 more
wiley   +1 more source

Experimental Evidence for the Involvement of PDLIM5 in Mood Disorders in Hetero Knockout Mice [PDF]

, 2013
BackgroundReports indicate that PDLIM5 is involved in mood disorders. The PDLIM5 (PDZ and LIM domain 5) gene has been genetically associated with mood disorders; it’s expression is upregulated in the postmortem brains of patients with bipolar disorder ...
Arinami Tadao, Horiuchi Yasue, Iijima Yoshimi, Ishiguro Hiroki, Ishikawa Maya, Kaito Nobuko, Tanabe Yoshiko, 有波 忠雄, 飯嶋 良味   +8 more
core   +1 more source

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María, Borges, Gisela, Micó Segura, Juan Antonio, Neto, Fani L., Torres-Sanchez, Sonia   +4 more
core   +4 more sources

Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration

ChemistryOpen, Volume 14, Issue 12, December 2025.
Incorporating deep eutectic solvents into polymer‐based drug delivery systems (DDS) offers a sustainable route to enhance solubility, modify drug release, and create dual‐function carriers. This review explores how DES influence polymer structures and DDS performance, highlighting future prospects in personalized, responsive pharmaceutical technologies.
Nining Nining, Yoga Windhu Wardhana, Taofik Rusdiana, Hariyanti Hariyanti   +3 more
wiley   +1 more source

Experience Of Medical Treatment With Desmopressin And Imipramine In Children With Severe Primary Nocturnal Enuresis In Taiwan

Research and Reports in Urology, 2019
Thomson T Tai,1,2 Brent T Tai,2,3 Yu-Jun Chang,2 Kuo-Hsuan Huang4,5 1Loyola University Chicago, Stritch School of Medicine, Maywood, IL, USA; 2Department of Epidemiology and Biostatistics, Changhua Christian Hospital, Changhua, Taiwan; 3Burrell College ...
Tai TT, Tai BT, Chang YJ, Huang KH
doaj  

Efficacy and Acceptability of Licensed and Off‐Label Pharmacological Interventions for Insomnia in Patients With Severe Mental Illness: A Systematic Review and Meta‐Analysis of Randomised Trials

Acta Psychiatrica Scandinavica, Volume 152, Issue 6, Page 405-421, December 2025.
ABSTRACT Background A wide range of drugs is used to alleviate insomnia symptoms in individuals with severe mental illness (SMI), including licensed drugs and sedating drugs prescribed off‐label. Yet, no review has gathered the evidence on illness‐specific or transdiagnostic outcomes of pharmacological interventions for insomnia.
Nina Friis Bak Fuglsang, Nanna Marker Madsen, Søren Lundorff Jacobsen, Julie Eg Frøkjær, Nicolai Ladegaard, Marc Alberg Sørensen, Christoph U. Correll, Christian Otte, Mikkel Højlund, Ole Köhler‐Forsberg   +9 more
wiley   +1 more source

Delphi Consensus Among French Obesity Experts on Clinical Recommendations for Drug Prescription in Patients With Severe Obesity

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Introduction Although the physiologic alterations seen in obesity often affect the pharmacokinetics and pharmacodynamics of drugs, most clinical trials do not consider these aspects specifically for this population. To date, there is no list of potentially inappropriate medications for patients living with obesity. The aim of this study was to
Sarah Berdot, Germain Perrin, Emmanuel Disse, Armelle Arnoux, Eric Bertin, Anne‐Laure Borel, Marie‐Claude Brindisi, Arnaud De Luca, Edouard‐Jules Laforgue, Jean‐Daniel Lalau, Yann Matussiere, Emilie Montastier, Agnès Sallé, Bérénice Segrestin, Valentine Suteau, French Hospital Expert Panel, Sebastien Czernichow, Brigitte Sabatier   +17 more
wiley   +1 more source

Effect of Local and Application of Amitriptyline and Imipramine on Teeth with Irreversible Pulpitis Failed Pulpal Anesthesia: A Randomized, Double-blind, Controlled Trial

Dental Hypotheses, 2016
Introduction: To evaluate the analgesic effect of amitriptyline and imipramine after local application on the dentine of “hot teeth” with failed pulpal anesthesia.
Mohsen Aminsobhani, Naghmeh Meraji, Abdollah Ghorbanzadeh, Majid Ajami, Seied Ali Seiedi Hoseini, Mohammad J Kharazifard   +5 more
doaj   +1 more source

Imipramine induces hyperactivity in rats pretreated with ouabain: Implications to the mania switch induced by antidepressants [PDF]

, 2021
Samira S. Valvassori, José H. Cararo, Carlos Augusto P. Marino, Taise Possamai‐Della, Camila L. Ferreira, Jorge M. Aguiar‐Geraldo, Gustavo C. Dal‐Pont, João Quevedo   +7 more
openalex   +1 more source

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, Volume 118, Issue 5, Page 994-1014, November 2025.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source