Results 51 to 60 of about 32,815 (232)

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

α2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment [PDF]

, 2010
Slow-onset adaptive changes that arise from sustained antidepressant treatment, such as enhanced adult hippocampal neurogenesis and increased trophic factor expression, play a key role in the behavioral effects of antidepressants.
Bartlett, Perry, Fernandes, Kimberly, Hein, Lutz, Jha, Shanker, Jhaveri, Dhanisha, Ladiwala, Uma, Marathe, Swananda V., Muthig, Verena, Rommelfanger, Karen, Vadodaria, Krishna C., Vaidya, Vidita A., Weinshenker, David, Yanpallewar, Sudhirkumar U.   +12 more
core   +1 more source

Did the French pregnancy pictogram change antiseizure medication use during pregnancy?

Epilepsia, EarlyView.
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo, Christine Damase‐Michel, Marie Denuelle, Sébastien Boulogne, Laurane Delteil, Monica Saucedo, Catherine Deneux‐Tharaux, Isabelle Lacroix   +7 more
wiley   +1 more source

Incontinência do choro e infarto protuberancial unilateral Incontinence of crying and unilateral pontine infarct

Arquivos de Neuro-Psiquiatria, 1995
O presente estudo trata do caso de um paciente que apresentou incontinência do choro e hemiplegia direita por infarto ventroprotuberancial paramediano detectado pela RNM.
Ricardo de Oliveira-Souza, Wagner Martignoni de Figueiredo, Pedro ângelo Andreiuolo   +2 more
doaj   +1 more source

Bee venom enhances dopaminergic function and behavioral recovery in a murine model of Parkinson's disease

Neuroprotection, EarlyView.
Experimental design and behavioral outcomes of bee venom treatment in a murine model of Parkinson's disease. Mice received an intrastriatal injection of 6‐OHDA into the right hemisphere to induce dopaminergic degeneration. Animals were subsequently treated with l‐DOPA/carbidopa, with or without bee venom (BV) administered intraperitoneally.
Silvia Josefina López‐Pérez, Marco Antonio Noriega‐Ruiz, Alma Karen Lomeli‐Lepe   +2 more
wiley   +1 more source

The Paroxetine 352 Bipolar Study Revisited: Deconstruction of Corporate and Academic Misconduct [PDF]

, 2019
Medical ghostwriting is the practice in which pharmaceutical companies engage an outside writer to draft a manuscript submitted for publication in the names of “honorary authors,” typically academic key opinion leaders.
Amsterdam, Jay D., McHenry, Leemon
core  

Completion rates of anterior and posterior continuous curvilinear capsulorrhexis in pediatric cataract surgery for surgery performed by trainee surgeons with the use of a low-cost viscoelastic

Indian Journal of Ophthalmology, 2012
Context : Pediatric cataract surgery is traditionally done with the aid of high-molecular-weight viscoelastics which are expensive. It needs to be determined if low-cost substitutes are just as successful.
R Muralidhar, G S Siddalinga Swamy, P Vijayalakshmi   +2 more
doaj   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Associations between anxiety, body mass index, and sex hormones in women [PDF]

, 2019
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.
Bae, Y., Ceglarek, U., Engel, C., Enzenbach, C., Glaesmer, H., Hinz, A., Kratzsch, J., Luck, T., Pabst, A., Riedel-Heller, S., Sacher, J., Stanik, J., Stanikova, D., Thiery, J., Wirkner, K.   +14 more
core   +2 more sources

Study of the β-Cyclodextrin Imipramine Hydrochloride Inclusion Complex and Determination of its Stability Constant (K) by UV-Visible Spectroscopy

E-Journal of Chemistry, 2007
In this research, the interactions of imipramine hydrochloride drug with β- cyclodextrin and the stability constant (K) of the inclusion complex formed between them were investigated by using UV-visible spectroscopy.
Alamdar Ashnagar, Nahid Gharib Naseri, Bita Khanaki   +2 more
doaj   +1 more source