Results 61 to 70 of about 1,178,558 (261)

Correlation analyses between platelet parameters, n = 581.

, 2014
IPF: Immature platelet fraction, IPC: Immature platelet count, MPV: Mean platelet volume.PC: Platelet count, PDW: Platelet distribution width, P-LCR: Platelet large cell ratio.
Steen Dalby Kristensen (447767), Anne-Mette Hvas (447765), Sanne Bøjet Larsen (447766), Erik Lerkevang Grove (447768)   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Platelet-related parameters at initial diagnosis for predicting the risk of chronicity in children with newly diagnosed immune thrombocytopenia

Frontiers in Pediatrics
ObjectiveTo investigate the clinical value of platelet-related parameters and clinical characteristics at initial diagnosis in predicting the risk of progression to chronic disease in children with newly diagnosed immune thrombocytopenia (ITP), and to ...
Shuxian Zheng, Jing Liang, Wen Jiang, Ran Han, Xiaofei Guo   +4 more
doaj   +1 more source

Immature cell fractions after cessation of chronic P2Y12-inhibition in patients with coronary artery diseases

Platelets, 2021
Changes in circulating cell populations may promote ischemic events that occur soon after discontinuation of P2Y12-inhibition. The aim of the study was to track the course of thrombopoietic and erythropoietic cells in patients with coronary artery ...
Bernhard Jäger, Kris G. Vargas, Paul M. Haller, Stefan Stojkovic, Christoph C. Kaufmann, Matthias Freynhofer, Peter Quehenberger, Oswald Wagner, Johann Wojta, Kurt Huber   +9 more
doaj   +1 more source

Changes in Platelet Function in Preterm Newborns with Prematurity Related Morbidities

Children, 2022
Platelet indices represent useful biomarkers to express the thromboembolic status, inflammatory response, and oxidative stress in preterm newborns.
Irina Franciuc, Elena Matei, Mariana Aschie, Anca Mitroi, Anca Chisoi, Ionut Poinareanu, Nicolae Dobrin, Andreea Georgiana Stoica, Traian Virgiliu Surdu, Mihaela Manea, Sebastian Topliceanu, Georgeta Camelia Cozaru   +11 more
doaj   +1 more source

Patients With Previous Definite Stent Thrombosis Have a Reduced Antiplatelet Effect of Aspirin and a Larger Fraction of Immature Platelets

, 2010
ObjectivesThis study sought to evaluate the platelet response to aspirin and the immature platelet fraction in patients with previous stent thrombosis (ST).BackgroundST is a potentially fatal complication of coronary stenting. A reduced platelet response
Wulff, Lise Nielsen, Hansen, Hans-Henrik Tilsted, Lise N. Wulff, Würtz, Morten, Steen D. Kristensen, Morten Würtz, Erik L. Grove, Anne K. Kaltoft, Jensen, Lisette O; id_orcid, Hvas, Anne-Mette, Grove, Erik, Kaltoft, Anne, Kristensen, Steen Dalby, Anne-Mette Hvas, Hans H. Tilsted, Lisette O. Jensen   +15 more
core   +1 more source

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo, Zahi Touma, Laura Whittall Garcia, Dafna D. Gladman, Behdin Nowrouzi‐Kia   +4 more
wiley   +1 more source

Assessment of medullary response through cellular immaturity parameters in patients undergoing hematopoietic stem cell transplantation [PDF]

Einstein (São Paulo)
Objective: This study aimed to evaluate relative immature platelet fraction (IPF%), absolute immature platelet fraction (A-IPF), and relative immature reticulocyte fraction (IRF%) as biomarkers of bone marrow recovery after hematopoietic stem cell ...
Bruno Gabriel Nardini Fogo, Iracema Esteves, Nelson Hamerschlak, Carolina Bonet Bub, Rosana Moreira Cosentino Penteado, Andréa Aparecida Rocco Vilarinho, João Carlos de Campos Guerra   +6 more
doaj   +2 more sources

Correction for effect of cold storage on immature platelet fraction

Journal of Clinical Laboratory Analysis, 2010
AbstractIt is common practice to store samples and measure the immature platelet fraction (IPF) only when the initial standard complete blood count and the blood smear indicate thrombocytopenia. However, the cold storage introduces an inherent error in the %IPF.
Andrew, Osei-Bimpong, Mohammad, Saleh, Martha, Sola-Visner, John, Widness, Peter, Veng-Pedersen   +4 more
openaire   +3 more sources