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Immature platelets in COVID-19

open access: yesPlatelets, 2023
Platelets play a critical role in immune response. Coronavirus disease 2019 (COVID-19) patients with a severe course often show pathological coagulation parameters including thrombocytopenia, and at the same time the proportion of immature platelets ...
Monika Wolny   +3 more
doaj   +4 more sources

Influence of Diagnosis of Venous Thromboembolism on Immature Platelets, Absolute Platelet Count and Platelet Aggregation Over Time

open access: yesPlatelets, 2021
The extent of the involvement of platelets in venous thromboembolisms (VTE) is still not fully understood. Immature platelets are large, RNA-rich, prothrombotic platelets.
Isabell Bernlochner   +2 more
exaly   +3 more sources

Immature Platelets and Platelet Reactivity in Patients with COVID-19 [PDF]

open access: yesClinical and Applied Thrombosis/Hemostasis
Coronavirus disease 2019 (COVID-19) is associated with a high incidence of thromboembolic events, both venous and arterial. There are currently no specific clinical or laboratory markers to guide antithrombotic therapy for COVID-19 patients.
Yulia Balmakov BMSc   +7 more
doaj   +4 more sources

Age-Dependent Surface Receptor Expression Patterns in Immature Versus Mature Platelets in Mouse Models of Regenerative Thrombocytopenia

open access: yesCells, 2023
Aging is a multifaceted process that unfolds at both the individual and cellular levels, resulting in changes in platelet count and platelet reactivity.
Anita Pirabe   +6 more
doaj   +2 more sources

Immature platelets and cardiovascular events in patients with stable coronary artery disease

open access: yesPlatelets, 2023
Many patients with coronary artery disease (CAD) have reduced the effect of aspirin, which may partly be explained by immature platelets. We aimed to investigate whether immature platelet markers can predict cardiovascular events in a large cohort of ...
Oliver Buchhave Pedersen   +4 more
doaj   +2 more sources

Reticulated Platelets—Which Functions Have Been Established by In Vivo and In Vitro Data?

open access: yesCells, 2021
Reticulated platelets (RP) are the youngest platelet fraction released into the circulation. These immature platelets have increased RNA content, a larger cell volume, more dense granules, higher levels of surface activation markers and are thought to be
Muataz Ali Hamad   +4 more
doaj   +2 more sources

Immature platelets: A useful tool for thrombocytopenia etiology classification in adults [PDF]

open access: yesHematology, Transfusion and Cell Therapy
Introduction: The etiology of thrombocytopenia is diverse with heterogenous clinical manifestations which demand the correct diagnosis and appropriate management. The immature platelet fraction is associated with new platelet release from the bone marrow
Raphael Ferreira Pimentel   +4 more
doaj   +2 more sources

Immature platelets and antiplatelet therapy response to aspirin in Kawasaki disease [PDF]

open access: yesDrug Design, Development and Therapy, 2018
Lei Pi,1,* Di Che,1,* Haifeng Long,2,3,* Zhenzhen Fang,4 Jiawen Li,1 Shuyi Lin,2 Yunfeng Liu,2 Meiai Li,2 Lijuan Bao,2 Wenli Li,2 Yuan Zhang,2 Qiulian Deng,2 Techang Liu,5 Li Zhang,5 Xiaoqiong Gu1,2 1Department of Clinical Biological Resource Bank ...
Pi L   +14 more
doaj   +2 more sources

Immature platelet fraction and reticulated platelet parameters as potential indicators of bone-marrow-related platelet production in dogs and cats: A scoping review. [PDF]

open access: yesPLoS ONE
BackgroundEvaluating bone marrow is an invasive and expensive procedure that frequently necessitates sedation or anesthesia in dogs and cats. The immature platelet fraction (IPF(and related immature or reticulated platelet parameters, has been suggested ...
Mahmood Ahmadi-Hamedani, Kimia Satari
doaj   +2 more sources

Advanced Flow Cytometry Using the SYTO-13 Dye for the Assessment of Platelet Reactivity and Maturity in Whole Blood

open access: yesMethods and Protocols, 2023
Newly produced immature platelets are larger, contain higher amounts of residual RNA, and are more reactive than mature platelets. Flow cytometry using the SYTO-13 dye is a method for the subdivision of immature platelets from mature platelets based on ...
Oliver Buchhave Pedersen   +5 more
doaj   +1 more source

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