Results 31 to 40 of about 237,408 (289)

Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death [PDF]

, 2003
Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages.
Jones, David B., Simon B. Brown, Brown, Simon B, Murray C.H. Clarke, David B. Jones, Savill, John, Brendon S. Noble, Clarke, Murray C H, Noble, Brendon S, John Savill, Brown, Simon B., Clarke, Murray C.H., Noble, Brendon S.   +12 more
core   +1 more source

Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]

, 1998
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Welsch, Ulrich, Heindl, Bernhard, Zahler, Stefan, Becker, Bernhard F.   +3 more
core   +1 more source

Immature Platelet Level in Stable Coronary Heart Disease (CHD) Patients with Diabetes Mellitus compared to Stable CHD Patients without Diabetes Mellitus [PDF]

, 2020
Coronary heart disease (CHD) causes high mortality and morbidity in many countries. Immature platelet reactivity is one of the major causes of CHD thrombus formation due to its larger size and stronger aggregation properties than normal platelets. Though
D R Balti, -, D N Asmarani, -, B B Dharmadjati, -, Andrianto, -   +3 more
core   +1 more source

Influence of diagnosis of venous thromboembolism on immature platelets, absolute platelet count and platelet aggregation over time

, 2020
The extent of the involvement of platelets in venous thromboembolisms (VTE) is still not fully understood. Immature platelets are large, RNA-rich, prothrombotic platelets.
Anja Stundl (6449207), Tareq Ibrahim (5269850), Isabel Wustrow (8746191), Karl-Ludwig Laugwitz (226421), Christian Bradaric (7873640), Nicolas Langwieser (8746197), Peter B. Luppa (8746200), Dario Bongiovanni (8307699), Christopher Ebner (8746194), Bernhard Haller (344426), Isabell Bernlochner (8746203)   +10 more
core   +1 more source

Annexin V binding to platelets is agonist, time and temperature dependent [PDF]

, 2010
Platelets bind annexin V when stimulated with combinations of platelet agonists such as collagen and thrombin. Previous studies have demonstrated significant heterogeneity of platelets binding annexin V.
Dunne, Eimear, Ramström, Sofia,, O'Neill, Sarah, Dunne, Eimear,, Ramström, Sofia, Kenny, Dermot,, Kenny, Dermot, O'Neill, Sarah,   +7 more
core   +1 more source

Immature platelet fraction in hypertensive pregnancy

Platelets, 2015
Imbalance in hemostatic mechanisms can occur during pregnancy with a tendency for hypercoagulability and increased thrombosis risk. Pregnant women with hypertensive disorder, especially preeclampsia, show alterations in platelet indexes. Immature platelet fraction (IPF) has been suggested as a sensitive index for monitoring changes in platelet ...
Daniela, Moraes, Terezinha Paz, Munhoz, Bartira E, Pinheiro da Costa, Marta Ribeiro, Hentschke, Fernando, Sontag, Luiza, Silveira Lucas, Giovani, Gadonski, Ivan Carlos, Antonello, Carlos E, Poli-de-Figueiredo   +8 more
openaire   +2 more sources

Influence of antiretroviral therapy and cardiovascular disease on the immature platelet fraction in patients living with HIV

Platelets, 2020
Cardiovascular disease is an important contributor to morbidity and mortality in people living with HIV . The immature platelet fraction (IPF) is increased in HIV-negative patients with cardiovascular disease and evidence suggests that an enlarged IPF is
A. Goedel, S. Müller, C. Schwerdtfeger, A. Zink, S. Noe, D. Bongiovanni, B. Haller, C. D. Spinner, I. Bernlochner   +8 more
doaj   +1 more source

Immature cell fractions after cessation of chronic P2Y12-inhibition in patients with coronary artery diseases

Platelets, 2021
Changes in circulating cell populations may promote ischemic events that occur soon after discontinuation of P2Y12-inhibition. The aim of the study was to track the course of thrombopoietic and erythropoietic cells in patients with coronary artery ...
Bernhard Jäger, Kris G. Vargas, Paul M. Haller, Stefan Stojkovic, Christoph C. Kaufmann, Matthias Freynhofer, Peter Quehenberger, Oswald Wagner, Johann Wojta, Kurt Huber   +9 more
doaj   +1 more source

Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry [PDF]

, 2021
Circulating large “preplatelets” undergo fission via barbell platelet intermediates into two smaller, mature platelets. In this study, we determine whether preplatelets and/or barbells are equivalent to reticulated/immature platelets by using ImageStream
Nicolson, Phillip L. R., Watson, Steve P, Watson, Steve P., Kemble, Sam, Lowe, Gillian, Kemble, Samuel, Nicolson, Phillip LR; id_orcid, Senis, Yotis, Dalby, Amanda, Lowe, Gillian C, Thomas, Steven G, Thomas, Steven; id_orcid, Nicolson, Phillip L R, Nicolson, Pip; id_orcid, Harrison, Paul; id_orcid, Watson, Steve; id_orcid, Thomas, Steven G.; id_orcid, Harrison, Paul, Watson, Steve P; id_orcid, Lowe, Gillian C., Thomas, Steven G., Phillip L. R. Nicolson, Steve P. Watson, Yotis Senis, Amanda Dalby, Samuel Kemble, Paul Harrison, Gillian C. Lowe, Steven G. Thomas, Gillian C Lowe, Steve P Watson, Phillip LR Nicolson, Sam Kemble   +32 more
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What can we learn from senescent platelets, their transcriptomes and proteomes? [PDF]

, 2023
Research into the natural aging process of platelets has garnered much research interest in recent years, and there have long been associations drawn between the proportion of newly formed platelets in the circulation and the risk of thrombosis. However,
Vadgama, A, Timothy D. Warner, Armstrong, PC, Allan, HE, Ami Vadgama, Warner, TD, Harriet E. Allan, Paul C. Armstrong   +7 more
core   +1 more source