Results 91 to 100 of about 237,408 (289)

Platelets /

, 2007
PLATELETS is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology
Michelson, Alan D.
core  

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Composition and synthesis of glycolipids in megakaryocytes and platelets: differences in synthesis in megakaryocytes at different stages of maturation

Journal of Lipid Research, 1990
The composition and synthesis of megakaryocyte and platelet glycolipids were compared since these lipids are thought to be important for biologic activities such as adhesion and maturation. Highly purified guinea pig megakaryocytes at different stages of
PK Schick, XL He
doaj   +1 more source

Investigating GABA and its function in platelets as compared to neurons

, 2009
We have recently suggested that platelets could be used as a model for neuronal receptors. In this paper we have investigated γ-aminobutyric acid (GABA) metabolism and GABA receptors in platelets and in cultured neurons to see whether platelets' GABA ...
Kaneez, FS, Saeed, SA, Fatima Shad Kaneez, Sheikh Arshad Saeed   +3 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Platelet Adhesion on Commercially Pure Titanium Plates in Vitro II. Immunofluorescence Visualization of PDGF-B, TGFβ1, and PPARγ Released from Activated Adherent Platelets

Dentistry Journal, 2019
Recent progress in the industrial development of dental implants has improved their surface bio-affinity, while clinical implantologists attempt to improve it through coating with various compounds, including platelet-rich plasma (PRP) in clinical ...
Tetsuhiro Tsujino, Akira Takahashi, Taisuke Watanabe, Kazushige Isobe, Yutaka Kitamura, Kazuhiro Okuda, Koh Nakata, Tomoyuki Kawase   +7 more
doaj   +1 more source

High fragmentation in platelet concentrates impacts the activation, procoagulant, and aggregatory capacity of platelets

, 2023
Platelets are transfused to patients to prevent bleeding. Since both preparation and storage can impact the hemostatic functions of platelets, we studied platelet concentrates (PCs) with different initial composition in regard to platelet fragmentation ...
Dermot Kenny, Alshamari, Aseel,, Sandgren, Per, Mohammad R. Abedi (14394616), Vasilache, Ana-Maria, Abedi, MR, Tynngard, N, Ramstroem, S, Mohammad R. Abedi, Ramström, Sofia,, Tynngård, Nahreen,, Abedi, Mohammad R.,, Kenny, Dermot, Sofia Ramström (808839), Vasilache, Ana-Maria,, Per Sandgren, Sofia Ramström, Vasilache, Ana Maria,, Aseel Alshamari (14394607), Ana Maria Vasilache (14394613), Tynngård, Nahreen, Kenny, Dermot,, Sandgren, P,, Vasilache, AM, Aseel Alshamari, Abedi, Mohammad R., Ana Maria Vasilache, Nahreen Tynngård (686725), Dermot Kenny (202554), Alshamari, A, Ramström, Sofia, Kenny, D, Per Sandgren (14394610), Nahreen Tynngård, Sandgren, Per,, Alshamari, Aseel   +35 more
core   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

α-granule biogenesis: from disease to discovery

Platelets, 2017
Platelets are critical to hemostasis and thrombosis. Upon detecting injury, platelets show a range of responses including the release of protein cargo from α-granules.
Chang Hua Chen, Richard W. Lo, Denisa Urban, Fred G. Pluthero, Walter H. A. Kahr   +4 more
doaj   +1 more source

GAMMA-GLUTAMYL-TRANSFERASE ACTIVITY IN HUMAN PLATELETS - QUANTIFICATION OF ACTIVITY, ISOENZYME CHARACTERIZATION AND POTENTIAL CLINICAL RELEVANCE

, 1995
Gamma-glutamyltransferase (GGT) activity in human platelet sonicates was 13.6 u/g of protein (range: 7.9-25.0) in 13 healthy, non-smoking, female volunteers; corresponding values in 16 males were: 20.3 (10.1-26.0), These values differed significantly (p =
NWOSE, OM, GURDOL, F, MIKHAILIDIS, DP
core   +1 more source