Results 161 to 170 of about 237,408 (289)
Arthritis &Rheumatology, EarlyView.Objective Pathologic bone formation in ankylosing spondylitis (AS) is not fully reflected by systemic inflammation, limiting the utility of markers of inflammation for structural damage assessment. This study aimed to identify plasma protein signatures associated with structural damage severity in AS.
Tiantian Sun +9 more
wiley +1 more source
Arthroscopy Techniques, EarlyView.Abstract Meniscal allograft transplantation is a surgical solution for symptomatic meniscal deficiency aimed at restoring native knee biomechanics and tibiofemoral contact pressures with the goal of slowing the progression of osteoarthritis. Anatomic fixation of the meniscal root is essential to a successful outcome as this normalizes native ...
Megan E. Barney +5 more
wiley +1 more source
HaematologicaIn Primary Myelifibrosis (PMF) the platelets contribute to the vascular complication and fibrosis. We focused on the reticulated immature platelets as in PMF there is an increased platelet turnover. It also is reported that the reticulated platelets (RPs)
V. Vecchio, R. Cacciola, E. Cacciola.
doaj
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)
British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul +7 more
wiley +1 more source
Changes in the immature platelet fraction within ageing platelet concentrates
Journal of Thrombosis and Haemostasis, 2008 Albanyan, A +3 more
openaire +4 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves +7 more
wiley +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source