Results 191 to 200 of about 2,108,803 (258)

Single‐Vesicle Functional Nanophenotyping Reveals Heterogeneous PD‐L1 Accessibility in Triple‐Negative Breast Cancer

open access: yesSmall Methods, EarlyView.
Graphical Abstract. High‐speed atomic force microscopy enables real‐time, label‐free visualization of antibody interactions with individual extracellular vesicles. By quantifying binding frequency and dwell time, this approach reveals functional PD‐L1 accessibility that cannot be inferred from protein abundance alone, uncovering nanoscale heterogeneity
Reon Imakawa   +10 more
wiley   +1 more source

Emergent Innovation in Systemic Programme Design: Retrospective Reflections on the Development of a Student‐Centred Masters in Systems Thinking

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT Our theory of education, based on a systemic understanding of the subjective and intersubjective construction of knowledge, is that students are motivated to study what is most meaningful to them. Meaningfulness is grounded in the students' prior experiences, which are highly diverse.
Wendy J. Gregory, Gerald Midgley
wiley   +1 more source

Semester in Dialogue: A Systems Thinking Approach to Dialogue‐Based Higher Education at Simon Fraser University

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This paper addresses a gap in the application of systems thinking to higher education programme design. We use the Complexity Theory of Outcome Creation (CTOC), a structured model for working in complexity, to analyse Simon Fraser University's Semester in Dialogue (SiD)—an innovative undergraduate programme applying the ideas of dialogic ...
Diane T. Finegood   +2 more
wiley   +1 more source

Challenges and Opportunities for Theory-Grounded Data Visualization in Extended Reality. [PDF]

open access: yesIEEE Comput Graph Appl
Bueckle A   +9 more
europepmc   +1 more source

“Anytime, Anywhere”: Online Language Tutoring Platforms and the Rise of the (Im)Mobile Language Teacher

open access: yesTESOL Quarterly, EarlyView.
Abstract This article examines how online tutoring platforms (OTPs) have facilitated new forms of (im)mobility—and discourses of (im)mobility—among online English tutors. Drawing on semi‐structured interviews with online tutors, the article critically interrogates OTPs' primary selling point: that online tutors can work “anytime, anywhere.” While OTPs ...
Nate Ming Curran
wiley   +1 more source

Modeling the Paths from L2 Use and Socio‐Affective Variables to Communication Skills: A Mixed‐Methods Approach

open access: yesTESOL Quarterly, EarlyView.
Abstract Previous research demonstrated that communication anxiety reduces L2 learners' willingness to communicate and communication frequency, but left unexplored its impact on performance. The current mixed‐methods study investigated factors impacting L2 communication skills.
Debra M. Hardison
wiley   +1 more source

Student Perceptions of a Virtual Reality Animation for Teaching Absorption and Bioavailability in Pharmacology: A Mixed Methods Evaluation. [PDF]

open access: yesPharmacol Res Perspect
Berg JA   +12 more
europepmc   +1 more source

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