Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Animal experimental research on microstructural behavior on the hyaline arthroidal cartilage after immobilization and remobilization [PDF]
The degeneration of the articular cartilage after a period of immobilization was investigated. The experiment was carried out by the immobilization of the knee joints of rabbits. Even after remobilization there was an increase in the alterations.
Refior, H. J.
core +1 more source
Chia seeds oil ameliorate chronic immobilization stress-induced neurodisturbance in rat brains via activation of the antioxidant/anti-inflammatory/antiapoptotic signaling pathways. [PDF]
Sci Rep, 2023 Khalifa NE +7 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan +12 more
wiley +1 more source
Effect of Broad-Spectrum Hemp Extract on Neurobehavioral Activity on the Immobilization Stress-Induced Model in Sprague Dawley Rats. [PDF]
ScientificWorldJournal, 2023 Shanmugasundaram D, Roza JM.
europepmc +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Comparative evaluation of natural neuroprotectives and their combinations on chronic immobilization stress-induced depression in experimental mice. [PDF]
3 Biotech, 2023 Ibrahim IM +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta +3 more
wiley +1 more source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. ПавловаIntroduction. Lipid metabolism disorders, caused by both excessive physical and psycho-emotional stress, and physical hypoxia, are important problems in the prevention and treatment of a number of diseases.The objective was to study the effect of 1,2,4 ...
N. B. Melnikova +6 more
doaj +1 more source
Effect of immobilization stress on the level of macroergic phosphates in the blood of rats [PDF]
The effect of immobilization for 1, 2, and 24 hours, and of daily (for 2 hours for 7 days) immobilization on the blood nucleotide (ATP, ADP, AMP) level was studied on 79 male rats.
Pudov, V. I., Sosenkov, V. A.
core +1 more source