Results 111 to 120 of about 75,693 (242)
Genes & Development, 1991 It has been shown previously that mutant p53 can act as an immortalizing gene when cotransfected into primary rat embryo fibroblasts along with a selectable marker.
D. Harvey, A. Levine
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Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival
Viruses, 2012 Epstein–Barr virus (EBV) immortalizes host cells as part of its latent mode of infection. As a result of this ability to promote cell proliferation and survival, EBV infection contributes to the development of several kinds of B-cell lymphomas and ...
L. Frappier
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International Journal of Ophthalmology, 2015 AIM: To investigate into the potential involvement of pyrin containing 3 gene (NLRP3), a member of the nucleotide-binding oligomerization domain-like receptors with cytosolic pattern recognition, in the host defense of corneas against viruses.
Shu-Long Wang +7 more
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Frontiers in Cellular and Infection MicrobiologyImmortalized bovine neuronal cell lines provide a reliable in vitro model for studying interactions with bovine infectious pathogens that target the host nervous system. Although we previously established an immortalized fetal bovine brain-derived FBBC-1
Rina Ikeda +5 more
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Histone H3 Lysine 79 Methyltransferase Dot1 Is Required for Immortalization by MLL Oncogenes
Cancer Research, 2010 Chimeric oncoproteins resulting from fusion of MLL to a wide variety of partnering proteins cause biologically distinctive and clinically aggressive acute leukemias.
Ming-jin Chang +7 more
semanticscholar +1 more source
, 2019 Inter-observer variability and cancer over-diagnosis are emerging clinical problems, and there is a strong necessity to support the standards histological and cytological evaluations by biochemical composition information.
Pelissier, Aurelien
core
Breast Tissue Biology Expands the Possibilities for Prevention of Age-Related Breast Cancers. [PDF]
, 2019 Preventing breast cancer before it is able to form is an ideal way to stop breast cancer. However, there are limited existing options for prevention of breast cancer.
Fresques, Tara +6 more
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The dual role of the DREAM/G2M pathway in non‐tumorigenic immortalization of senescent cells
FEBS Open BioAnti‐aging and tumorigenesis share common genes and pathways, and thus targeting these genes as part of anti‐aging interventions carries the risk of tumorigenesis. It is essential to understand the gene signatures that balance tumorigenesis and aging. To
Jie Tian +4 more
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A study of murine bone marrow cells cultured in bioreactors which create an environment which simulated microgravity [PDF]
Previous research indicated that mouse bone marrow cells could be grown in conditions of simulated microgravity. This environment was created in rotating bioreactor vessels. On three attempts mouse cells were grown successfully in the vessels.
Lawless, Brother Desales
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