Results 91 to 100 of about 75,693 (242)
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death [PDF]
, 2016 Sensing bacterial products in the cytosol of mammalian cells by NOD-like receptors leads to the activation of caspase-1 inflammasomes, and the production of the pro-inflammatory cytokines interleukin (IL)-18 and IL-1β.
Alix, E +7 more
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Construction and function validation of inducible immortalized gene integration vectors
Zhongguo shuxue zazhi[Objective] To construct inducible immortalization gene vectors for transfection into primary cells, enabling the establishment of a conditionally immortalized cell line that support their sustained cultivation and proliferation in vitro. [Methods] Using
YUE Wei +4 more
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Emerging roles of telomeric chromatin alterations in cancer [PDF]
, 2019 Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Biroccio, Annamaria +2 more
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Conditionally immortalized white preadipocytes: a novel adipocyte models⃞
Journal of Lipid Research, 2008 This study describes a novel approach to generate conditionally immortalized preadipocyte cell lines from white adipose tissue (IMWAT) that can be induced to differentiate into white adipocytes even after expansion in culture.
D.L. Morganstein +4 more
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Annals of the New York Academy of Sciences, 2004 Abstract:This article draws on ideas published in my “Intimations of Immortality” essay inScience(Vol. 288, No. 5463, p. 59, April 7, 2000) and my “Intimations of Immortality—The Ethics and Justice of Life Extending Therapies” in editor Michael Freeman'sCurrent Legal Problems(Oxford University Press 2002: 65‐97).
openaire +4 more sources
Microbiology SpectrumMacrophages are present in all vertebrate tissues and play a key role in both the prevention and pathogenesis of infectious diseases. In vitro cultures of macrophages provide a valuable tool for studying the innate immune functions of macrophages and ...
Rina Ikeda +5 more
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Taking the brakes off telomerase
eLife, 2015 Studies using human embryonic stem cells have revealed how common cancer-associated mutations exert their effect on telomerase after cells differentiate into more specialized cell types.
Kamila Naxerova, Stephen J Elledge
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BioTechniques, 2015 Reproducibility in life science is a hot button topic at the moment. Jeffrey Perkel examines the ways in which stem cell researchers are dealing with this issue in their work.
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Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro [PDF]
, 2004 Spermatogonia are the male germ stem cells that continuously produce sperm for the next generation. Spermatogenesis is a complicated process that proceeds through mitotic phase of stem cell renewal and differentiation, meiotic phase, and postmeiotic ...
Chen, TS +9 more
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