Belimumab for Immune-Mediated Necrotizing Myopathy Associated With Anti-SRP Antibodies: A Case Report and Retrospective Review of Patients Treated With Anti-B-Cell Therapy in a Single Center and Literature [PDF]
Beibei Cui +4 more
openalex +1 more source
Osmolytes as mediators of the muscle tissue’s responses to inflammation : emerging regulators of myositis with therapeutic potential [PDF]
Chronic inflammation of skeletal muscle tissues termed myositis is associated with inherited muscular dystrophy and with acquired inflammatory myopathy.
De Paepe, Boel
core +1 more source
Treatment and outcomes in necrotising autoimmune myopathy: an australian perspective [PDF]
Necrotising Autoimmune Myopathy (NAM) presents as a subacute proximal myopathy with high creatine kinase levels. It is associated with statin exposure, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibody, connective tissue diseases, signal ...
Ashton, C. +4 more
core +1 more source
Muscle MRI in immune-mediated necrotizing myopathy (IMNM): implications for clinical management and treatment strategies [PDF]
Laura Fionda +16 more
openalex +1 more source
Immune-mediated Necrotizing Myopathy in a Patient with Microscopic Polyangiitis
We herein report a case of immune-mediated necrotizing myopathy (IMNM) in a patient with microscopic polyangiitis (MPA). A 77-year-old Japanese woman presented with a 2-day history of proximal muscle weakness and myalgia, with elevated serum creatinine kinase (CK) levels.
Umemoto, Daichi +8 more
openaire +2 more sources
Anti-HMGCR myopathy mimicking facioscapulohumeral muscular dystrophy [PDF]
Introduction Statin use can lead to various muscle-related issues, including benign creatine kinase (CK) elevations, myalgias, toxic myopathies, rhabdomyolysis, and immune-mediated necrotizing myositis (IMNM), which primarily affects ...
Atiya, Monika +5 more
core +1 more source
Histopathology of the muscle in rheumatic diseases. [PDF]
The presence of muscular symptoms is common in rheumatological clinical practice, but often the differential diagnosis between muscular involvement in connective tissue diseases, vasculitis and drug-induced myopathy may be difficult.
A. Tripoli +4 more
core +2 more sources
Case Report: Immune Mediated Necrotizing Myopathy With IgG Antibodies to 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase (HMGCR) May Present With Acute Systolic Heart Failure [PDF]
Malik Ghannam, Georgios Manousakis
openalex +1 more source
A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi +13 more
core +1 more source

