Results 141 to 150 of about 6,308 (185)

Seronegative Immune-Mediated Necrotizing Myopathy Presenting as Acute Onset Quadriparesis

European Journal of Medical and Health Sciences
Immune-mediated necrotizing myopathy (IMNM) is a rare, rapidly progressive inflammatory myopathy that closely resemble Guillain-Barré syndrome (GBS), making early diagnosis particularly challenging.
Soumia M, Sunita Aggarwal, Pradeep Kumar, R. Saran, Rahul Yadav, Riddhi   +5 more
semanticscholar   +1 more source

Anti‐Signal Recognition Particle Antibody‐Positive Immune‐Mediated Necrotizing Myopathy Diagnosed by Re‐Evaluation 40 Years After Symptom Onset

Neuropathology (Kyoto. 1993)
Immune‐mediated necrotizing myopathy (IMNM) is a frequent subtype of idiopathic inflammatory myopathies. Distinguishing juvenile‐onset IMNM from muscular dystrophy is often difficult, particularly when the disorder takes a chronic course.
Kentaro Yoshida, T. Adachi, Shigeaki Suzuki, Ichizo Nishino, Ritsuko Hanajima   +4 more
semanticscholar   +1 more source

Immune-mediated necrotizing myopathy: case report of a disease with uncommon clinical and histopathological features

São Paulo Medical Journal
Introduction: Immune-mediated necrotizing myopathy (IMNM) has distinct subtypes associated with specific autoantibodies. Mitochondrial dysfunction-associated polymyositis may represent an atypical form of inclusion body myositis and differs from IMNM in ...
Pedro Barros Lemos, T. P. Fagundes, Louise Makarem Oliveria, J. Kouyoumdjian, C. F. R. Sobreira   +4 more
semanticscholar   +1 more source

Spectrum of immune-mediated necrotizing myopathies and their treatments

Current Opinion in Rheumatology, 2016
Purpose of reviewThis review aims to describe the spectrum of clinical, histological, and serological features in patients with immune-mediated necrotizing myopathies (IMNMs).Recent findingsAutoantibodies recognizing the signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) define two unique subtypes of necrotizing ...
Iago, Pinal-Fernandez, Andrew L, Mammen
openaire   +2 more sources

Paraneoplastic anti-SRP antibody positive immune-mediated necrotizing myopathy in a young female associated with lymphoma.

Journal of Neuromuscular Diseases
We report an exceptional case of immune-mediated necrotizing myopathy (IMNM) associated with anaplastic large cell lymphoma (ALCL). A 26-year-old female patient presented with subacute bilateral proximal muscle weakness and myalgia, highly elevated ...
J. Heugenhauser, F. Pauli, Günther Stockhammer, Andreas Chott, C. Feistritzer, D. Egle, Benjamin Henninger, J. Wanschitz   +7 more
semanticscholar   +1 more source

Immune-Mediated Necrotizing Myopathy: Update on Diagnosis and Management

Current Rheumatology Reports, 2015
The idiopathic inflammatory myopathies (IIMs) comprise a group of autoimmune disorders that target skeletal muscle. They are characterized by typical laboratory and clinical features including muscle weakness, elevated muscle enzymes, characteristic histopathology of muscle biopsies, as well as electromyography abnormalities.
Pari, Basharat, Lisa, Christopher-Stine
openaire   +2 more sources

Successful methotrexate and rituximab combination therapy for a Taiwanese patient with anti-signal recognition particle antibody-positive immune-mediated necrotizing myopathy: A case report.

Modern Rheumatology Case Reports
We report the successful use of methotrexate (MTX) and rituximab in a Taiwanese patient with anti-signal recognition particle (SRP) antibody-positive immune-mediated necrotizing myopathy (IMNM) refractory to conventional therapy.
Haruka Toshina, Shigeru Iwata, Ryo Matsumiya, Yoshiaki Nakayama, Ryuta Iwamoto, Katsuichi Miyamoto, Takao Fujii   +6 more
semanticscholar   +1 more source

Anti-signal recognition particle immune-mediated necrotizing myopathy: a diagnostic challenge

São Paulo Medical Journal
Introduction: Immune-mediated necrotizing myopathies (IMNM) represent a severe group of idiopathic inflammatory myopathies, histologically marked by muscle fiber necrosis with inflammatory infiltrates.
Lucas Lot e Silva, Fabiano de Melo Peixoto, Lucas Gabriel de Oliveira Bastos   +2 more
semanticscholar   +1 more source

Abstract 4370073: A Delayed Diagnosis of Anti-HMG-CoA Reductase Immune-Mediated Necrotizing Myopathy

Circulation
Description of Case: A 62-year-old male with a past medical history of chronic kidney disease stage 4, hyperlipidemia, and lacunar stroke presented with a 1-month history of worsening painless proximal muscle weakness.
Reshma V. Jadhav, Arush Shekar, Zack K Westenhaver, Amith Skandhan   +3 more
semanticscholar   +1 more source

Distinct phenotype and prognosis of immune-mediated necrotizing myopathy based on clinical-serological-pathological classification.

Rheumatology
OBJECTIVE The aim of the study was to investigate the characteristics and prognosis of patients with immune-mediated necrotizing myopathy (IMNM) based on clinical, serological and pathological classification.
Hongxia Yang, Lining Zhang, X. Tian, Wenli Li, Qingyan Liu, Q. Peng, Wei Jiang, Guochun Wang, Xin Lu   +8 more
semanticscholar   +1 more source