Results 21 to 30 of about 5,479,910 (356)

Increasing Endurance of an Autonomous Robot using an Immune-Inspired Framework [PDF]

open access: yes, 2011
This paper describes the implementation of an online immune-inspired framework to help increase endurance of an autonomous robot. Endurance is defined as the ability of the robot to exert itself for a long period of time.
Howe, Joe M., Mokhtar, Maizura
core   +1 more source

Binding Affinity Measurement of Antibodies from Crude Hybridoma Samples by SPR

open access: yesBio-Protocol, 2014
Surface Plasmon Resonance (SPR) is widely used to generate kinetic and affinity information on specific interactions between biomolecules. This technique is label-free and monitors the binding event in real-time. It is generally used for characterization
Dorin Ndao   +5 more
doaj   +1 more source

The Application of Evidence-Based Medicine in Individualized Medicine

open access: yesBiomedicines, 2023
The fundamental aim of healthcare is to improve overall health of the population by providing state-of-the-art healthcare for individuals at an affordable cost. The foundation for this system is largely referred to as “evidence-based medicine”. Too often,
Peter Van de Vliet   +6 more
doaj   +1 more source

Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]

open access: yes, 2017
Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick   +12 more
core   +1 more source

Design of a titering assay for lentiviral vectors utilizing direct extraction of DNA from transduced cells in microtiter plates

open access: yesMolecular Therapy: Methods & Clinical Development, 2016
Using lentiviral vector products in clinical applications requires an accurate method for measuring transduction titer. For vectors lacking a marker gene, quantitative polymerase chain reaction is used to evaluate the number of vector DNA copies in ...
Michele E Murphy   +4 more
doaj   +1 more source

Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood [PDF]

open access: yes, 2013
The immune system is regulated by circadian clocks within the brain and immune cells. Environmental circadian disruption (ECD), consisting of a 6-h phase advance of the light:dark cycle once a week for 4 weeks, elevates the inflammatory response to ...
Adams, Kandis L.   +3 more
core   +2 more sources

Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats. [PDF]

open access: yes, 2008
The development of type 2 diabetes is accompanied by decreased immune function and the mechanisms are unclear. We hypothesize that oxidative damage and mitochondrial dysfunction may play an important role in the immune dysfunction in diabetes.
Hao, Jiejie   +8 more
core   +1 more source

Association between Sleep Duration and Left Ventricular Hypertrophy for Patients with Type 2 Diabetes Mellitus

open access: yesInternational Journal of Endocrinology, 2023
Objective. In this study, we aimed to estimate the impact of sleep duration on left ventricular hypertrophy (LVH) in type 2 diabetes mellitus (T2DM). Methods.
Lin Mu   +5 more
doaj   +1 more source

Parallelism and divergence in immune responses: a comparison of expression levels in two lakes [PDF]

open access: yes, 2014
Question: How do immune phenotypes differ between infected and uninfected wild individuals, and is the effect the same in different populations? Organisms: Threespine stickleback (Gasterosteus aculeatus) from two lake populations on the island of North ...
Ando   +43 more
core   +2 more sources

Frequent adaptive immune responses against arginase-1

open access: yesOncoImmunology, 2018
The enzyme arginase-1 reduces the availability of arginine to tumor-infiltrating immune cells, thus reducing T-cell functionality in the tumor milieu. Arginase-1 is expressed by some cancer cells and by immune inhibitory cells, such as myeloid-derived ...
Evelina Martinenaite   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy