A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Cell Surface Targeting of Heat Shock Protein gp96 Induces Dendritic Cell Maturation and Antitumor Immunity [PDF]
Hong Zheng +3 more
openalex +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
High Dietary Protein Exacerbates Hypertension and Renal Damage in Dahl SS Rats by Increasing Infiltrating Immune Cells in the Kidney [PDF]
Carmen De Miguel +2 more
openalex +1 more source
Profiling Tumor Infiltrating Immune Cells with CIBERSORT.
Binbin Chen +4 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system
Jennifer L. Matsuda +3 more
openalex +2 more sources
The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor [PDF]
Phillip Scheinberg +10 more
openalex +1 more source
PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung [PDF]
Torsten Goldmann +14 more
openalex +1 more source
Metabolism of immune cells in cancer
R. Leone, J. Powell
semanticscholar +1 more source

