Results 161 to 170 of about 14,522,121 (350)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Profiling Tumor Infiltrating Immune Cells with CIBERSORT.

open access: yesMethods in molecular biology, 2018
Binbin Chen   +4 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system

open access: green, 2008
Jennifer L. Matsuda   +3 more
openalex   +2 more sources

The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor [PDF]

open access: bronze, 2009
Phillip Scheinberg   +10 more
openalex   +1 more source

PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung [PDF]

open access: hybrid, 2021
Torsten Goldmann   +14 more
openalex   +1 more source

Metabolism of immune cells in cancer

open access: yesNature Reviews. Cancer, 2020
R. Leone, J. Powell
semanticscholar   +1 more source

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