Results 61 to 70 of about 177,775 (151)

A new frontier in treatment of advanced melanoma: Redefining clinical management in the era of immune checkpoint inhibitors

Human Vaccines & Immunotherapeutics, 2017
Immune checkpoint inhibitors have revolutionized treatment of advanced cutaneous melanoma. This group of novel therapeutic agents differs from other systemic treatments and has necessitated a new approach for several fundamental aspects of clinical ...
Oren Levine, Tahira Devji, Feng Xie
doaj   +1 more source

Pathomechanism of immune checkpoint inhibitors-induced cardiotoxicity

Medycyna Paliatywna
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that work by blocking CTLA-4, PD-1 or PD-L1 molecules. They help activate the immune system to recognize and eliminate cancer cells. Immune checkpoint inhibitors are monoclonal antibodies that
Agata Kornacka, Emilia Babula, Agnieszka Floriańczyk, Agata Prokopiuk, Katarzyna Kołodziejczyk, Tomasz Dzierżanowski   +5 more
doaj   +1 more source

Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab

Scientific Reports
The clinical success of immune checkpoint inhibitors has underscored the key role of the immune system in controlling cancer. Current FDA-approved immune checkpoint inhibitors target the regulatory receptor pathways of cytotoxic T-cells to enhance their ...
Nicholas Lorig-Roach, Nina M. Harpell, Rebecca M. DuBois   +2 more
doaj   +1 more source

Nanomaterials and immune checkpoint inhibitors in cancer immunotherapy: the synergistic innovation prospects

Frontiers in Immunology
Tumor cells can utilize the immune checkpoint pathway to inhibit T cell activation and evade the attack of tumor specific T cells. While immune checkpoint inhibitors (ICIs) competitively bind to checkpoint molecules to block checkpoint mediated ...
Jing Chen, Xue Cheng
doaj   +1 more source

Immune checkpoint inhibitor-related endocrinopathies

Journal of Translational Internal Medicine, 2022
Lu, Difei, Gao, Ying
openaire   +2 more sources

Immune Checkpoint Inhibitors in Penile Cancer

Future Science OA, 2021
Carlo Buonerba, Luca Scafuri, Ferdinando Costabile, Bruno D’Ambrosio, Simona Gatani, Pasquale Verolino, Rossella Di Trolio, Vincenzo Cosimato, Antonio Verde, Giuseppe Di Lorenzo   +9 more
openaire   +3 more sources

Advances in Immune Checkpoint Inhibitors for Cancer Treatment. [PDF]

Cancers (Basel)
Chen K, Zhu F, Li X, Yoshimura T.
europepmc   +1 more source

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series. [PDF]

Oncol Lett
Kato T, Mitsumura T, Tsuboi E, Nakahama H, Takahashi Y, Nei Y, Hanada S, Miyamoto A, Uruga H, Fujii T, Tamaoka M.   +10 more
europepmc   +1 more source

A systematic review of immune checkpoint inhibitors in endometrial cancer. [PDF]

Front Oncol
Zhu N, Zhang C.
europepmc   +1 more source

Pulmonary toxicity of immune checkpoint inhibitors. [PDF]

Breathe (Sheff)
Garvey S, Nadarajan P.
europepmc   +1 more source