Immune Checkpoint Inhibitors and Kidney Toxicity: Advances in Diagnosis and Management
Kidney Medicine, 2021 Immune checkpoint inhibitors are now approved for more than 50 indications, and increasing numbers of patients with advanced cancer are receiving immunotherapy.
Harish Seethapathy +2 more
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Cardiovascular outcomes and hospitalizations in Asian patients receiving immune checkpoint inhibitors: a population-based study [PDF]
, 2022 Immune checkpoint inhibitors (ICI) have known associations with cardiotoxicity. However, a representative quantification of the adverse cardiovascular events and cardiovascular attendances amongst Asian users of ICI has been lacking.
Liu, Tong +13 more
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Pathophysiology, diagnosis and management of cardiac toxicity induced by immune checkpoint inhibitors and BRAF and MEK inhibitors. [PDF]
, 2021 Immune checkpoint inhibitors (ICIs) and BRAF and MEK inhibitors (BRAFi/MEKi) have drastically improved the outcome of melanoma patients. ICIs can induce myocarditis, a rare immune related adverse event (irAE) with an estimated lethality of 50%.
Monney, P. +9 more
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Pulmonary Circulation, 2021 Immunologic risk factors contribute to endothelial dysfunction and development of pulmonary vascular disease. Immune checkpoint inhibitors, used as immunotherapies for malignancies, have a wide range of reported immune-related adverse events.
Ruben Mylvaganam +6 more
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Receipt of subsequent immune checkpoint inhibitors at progression among patients with solid tumors enrolled in clinical trials of adjuvant immune checkpoint inhibitors [PDF]
, 2022 : Purpose: Immune checkpoint inhibitors can induce long-term responses in metastatic cancer, thus determining how many patients on placebo control arms of adjuvant immune checkpoint inhibitors receive these drugs as standard of care at ...
Haslam, Alyson +2 more
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Operative management of immune checkpoint colitis following in-transit melanoma: Case report
Frontiers in Oncology, 2023 Immune checkpoint inhibitors are increasingly used as powerful anti-neoplastic therapies in the setting of melanoma. Colitis is a known complication of immune checkpoint inhibitors that if often medically managed.
Betzaira G. Childers +5 more
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Research Progress of Immune Checkpoint Inhibitors in Colorectal Cancer
Zhongliu Fangzhi Yanjiu, 2020 Tumor immunity is a new line of research for the treatment of patients with solid tumors, and negative regulators of the immune system called immune checkpoints play a key role in limiting antitumor immunologic responses.
ZHUANG Yuwen +3 more
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Research Progress of Immune Checkpoint Therapy on Colorectal Cancer
Zhongliu Fangzhi Yanjiu, 2021 At present, immunotherapy is in full swing in the treatment of non-small cell lung cancer, melanoma, bladder cancer and other tumor species, and its treatment methods are also diverse, including tumor vaccine treatment, adoptive T cell therapy, immune ...
CAO Qihua, XU Yanbo, XU Dong
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Management of the Cardiovascular Adverse Effects of Immune Checkpoint Inhibitors
, 2023 With the rising use of immune checkpoint inhibitors in oncologic treatment, many so called immune related adverse events have been described. The guidelines regarding management of hepatitis, gastritis and dermatitis have been well discussed in ...
Elsaygh, Hassan Nabil
core
Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series [PDF]
, 2023 Background While immune checkpoint inhibitors (ICIs) are associated with elevated cardiovascular risks, evidence of any association between ICIs and myocardial infarction (MI) was scarce, especially in Asians.
Tse, Gary +9 more
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