Results 111 to 120 of about 1,246,147 (266)

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Tax Evasion, Social Norms and Conditional Cooperation [PDF]

Tax Evasion; Social Norms; Conditional ...
Traxler, Christian
core  

Advances in protein ubiquitination modification and immune evasion of breast cancer

Frontiers in Cell and Developmental Biology
Protein ubiquitination is one type of post-translational modification that can alter many properties of the protein—stability, activity, subcellular location, binding affinity for other proteins, etc.
Yifan Wu, Yifan Wu, Jiangdong Jin, Jiangdong Jin, Xin Cheng, Xin Cheng, Ziyi Fu, Ziyi Fu, Hui Xie, Hui Xie   +9 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Tax Evasion and Competition [PDF]

Using a Cournot oligopoly model with an endogenous number of firms and evasion of indirect taxes, this paper shows that more intense competition may have the negative side-effect of eroding tax revenues by increasing tax evasion. This will be the case if
Marco Runkel, Laszlo Goerke
core  

PRRX1-OLR1 axis supports CAFs-mediated lung cancer progression and immune suppression

Cancer Cell International
Objective To investigate the mechanism by which cancer-associated fibroblasts (CAFs) affect the growth and immune evasion of lung cancer cells. Methods Initially, datasets comparing CAFs with normal fibroblasts were downloaded from the GEO dataset ...
Yunhao Sun, Kaijun Ying, Jian Sun, Yao Wang, Limin Qiu, Mingming Ji, Lin Sun, Jinjin Chen   +7 more
doaj   +1 more source

Protein O-fucosyltransferase 1 promotes PD-L1 stability to drive immune evasion and directs liver cancer to immunotherapy

Journal for ImmunoTherapy of Cancer
Background and aims The immunosuppressive tumor microenvironment (TME) plays an essential role in cancer progression and immunotherapy response. Despite the considerable advancements in cancer immunotherapy, the limited response to immune checkpoint ...
Fan Wang, Yu Tong, Qiang Xia, Linfeng Li, Wenyun Guo, Zijun Zhu, Qianyu Li, Yifei Qian, Songling Li, Yanfeng Liu   +9 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

A Multi-Agent Model of Tax Evasion with Public Expenditure [PDF]

We develop a model where heterogeneous agents maximize their individual utility based on (after tax) income and on the level of public expenditure (as in Cowell, Gordon, 1988).
Dino Rizzi, Paolo Pellizzari
core  

Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma

Frontiers in Immunology
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive malignancy characterized by a complex tumor microenvironment (TME) that plays a pivotal role in tumor initiation, progression, and immune evasion.
Xuri Zhao, Yaping Zhu, Youya He, Weiyan Gu, Qi Zhou, Bei Jin, Shenguo Chen, Haisheng Lin   +7 more
doaj   +1 more source