Results 211 to 220 of about 1,940,572 (373)

Tristetraprolin mediates immune evasion of mycobacterial infection in macrophages

FASEB BioAdvances
Immune evasion of Mycobacterium tuberculosis (Mtb) facilitates intracellular bacterial growth. The mechanisms of immune evasion, however, are still not fully understood.
Jiawei Wei, Huan Ning, Octavio Ramos‐Espinosa, Christopher S. Eickhoff, Rong Hou, Qinghong Wang, Mingui Fu, Ethan Y. Liu, Daping Fan, Daniel F. Hoft, Jianguo Liu   +10 more
doaj   +1 more source

Mast cells at the host–pathogen interface: host-protectionversusimmune evasion in leishmaniasis [PDF]

, 2004
Bhaskar Saha, Abulkader M Tonkal, Simon L. Croft, Sudeshna Roy   +3 more
openalex   +1 more source

Alterations of immune response of non-small lung cancer with azacytidine [PDF]

, 2013
Innovative therapies are needed for advanced Non-Small Cell Lung Cancer (NSCLC). We have undertaken a genomics based, hypothesis driving, approach to query an emerging potential that epigenetic therapy may sensitize to immune checkpoint therapy targeting
Baylin, Stephen B, Brahmer, Julie R, Brock, Malcolm V, Carvajal, Richard D, De Meyer, Tim, Du, Zhengzong, Easton, Keith, Easwaran, Hariharan, Jones, Peter A, Juergens, Rosalyn A, Koch, Alexander, Laird, Peter W, Mohammad, Helai P, Pardoll, Drew, Parsana, Princy, Rodgers, Kristen, Rudin, Charles M, Taube, Janis M, Topalian, Suzanne L, Tsai, Salina, Tykodi, Scott S, Van Criekinge, Wim, Vendetti, Frank, Wang, Wei, Weisenberger, Daniel J, Wrangle, John, Yen, Ray-Whay, Zahnow, Cynthia A   +27 more
core   +1 more source

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

Advanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He, Kai Yuan, Junming Pan, Shaoping Weng, Chaozheng Li, Yihong Chen, Jianguo He   +6 more
wiley   +1 more source

Pan-Cancer Proteogenomics Characterization of Tumor Immunity [PDF]

Despite the successes of immunotherapy in cancer treatment over recent decades, less than \u3c10%-20% cancer cases have demonstrated durable responses from immune checkpoint blockade.
Batra, Harsh, Calinawan, Anna, Cantley, Lewis C, Caruso, Francesca Pia, Ceccarelli, Michele, Charytonowicz, Daniel, Chowdhury, Shrabanti, Christianson, Karen E, Cieslik, Marcin, Clarke, Daniel J B, Clinical Proteomic Tumor Analysis Consortium, Deng, Eden Z, Evangelista, John Erol, Fenyö, David, Gillette, Michael A, González-Robles, Tania J, Gosline, Sara J C, Gümüş, Zeynep H, Hostetter, Galen, Huntsman, Emily M, Iavarone, Antonio, Johnson, Jared L, Kennedy, Jacob J, Klein, Robert J, Krek, Azra, Lazar, Alexander J, Lewis, David A, Li, Yize, Ma, Weiping, Ma\u27ayan, Avi, Mani, D R, Marino, Giacomo B, Nesvizhskii, Alexey I, Omenn, Gilbert S, Parra, Edwin Roger, Paulovich, Amanda G, Petralia, Francesca, Raso, Maria Gabriela, Reva, Boris, Robles, Ana I, Rykunov, Dmitry, Satpathy, Shankha, Sebra, Robert, Segura, Rossana Lazcano, Selvan, Myvizhi Esai, Song, Xiaoyu, Soundararajan, Rama, Tang, Ximing, Tignor, Nicole, Turhan, Berk, Wang, Joshua M, Wang, Pei, Wang, Ying, Whiteaker, Jeffrey R, Wiznerowicz, Maciej, Yaron, Tomer M, Yi, Xinpei, Zhang, Bing, Zhao, Lei   +58 more
core   +1 more source

AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun, Huazhen Xu, Guanming Lu, Ciqiu Yang, Xinya Gao, Jing Zhang, Xin Liu, Yongcheng Chen, Kun Wang, Jianping Guo, Jie Li   +10 more
wiley   +1 more source

Epstein–Barr Virus Encoded Interleukin-10 Inhibits HLA-Class I, ICAM-1, and B7 Expression on Human Monocytes: Implications for Immune Evasion by EBV

, 2002
Shahram Salek‐Ardakani, John R. Arrand, M. Mackett   +2 more
openalex   +1 more source

261. Immune Evasion in Gene Therapy [PDF]

, 2004
Rob C. Hoeben, Martine Ossevoort, Birgit M. Visser, Arnaud Zaldumbide, E I van der Voort, Diana J.M. van den Wollenberg, René E. M. Toes   +6 more
openalex   +1 more source

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements

Nature, 2021
Shang-Min Zhang, Wesley L. Cai, Xiaoni Liu, D. Thakral, Jiesi Luo, Lok-Hei Chan, M. McGeary, E. Song, K. Blenman, G. Micevic, S. Jessel, Yangyi Zhang, Mingzhu Yin, C. Booth, Lucia B. Jilaveanu, W. Damsky, M. Sznol, H. Kluger, A. Iwasaki, M. Bosenberg, Q. Yan   +20 more
semanticscholar   +1 more source

Mucous Permeable Nanoparticle for Inducing Cuproptosis‐Like Death In Broad‐Spectrum Bacteria for Nebulized Treatment of Acute Pneumonia

Advanced Science, EarlyView.
Copper‐based nanoparticles doped with BSO, and modified with PEG, not only can it increase the retention ability and mucosal penetration ability in the lungs, but also induce cuproptosis‐like death in bacteria and inhibit bacterial TCA cycle. It can also inhibit bacterial quorum sensing, clear biofilms, reduce bacterial virulence, and thus exert ...
Huiqun Hu, Shiyuan Hua, Feng Lu, Wenting Zhang, Zengwen Zhang, Jiarong Cui, Xiaoyue Lei, Jingyan Xia, Feng Xu, Min Zhou   +9 more
wiley   +1 more source