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Poxviruses and Immune Evasion

Annual Review of Immunology, 2003
Large DNA viruses defend against hostile assault executed by the host immune system by producing an array of gene products that systematically sabotage key components of the inflammatory response. Poxviruses target many of the primary mediators of innate immunity including interferons, tumor necrosis factors, interleukins, complement, and chemokines ...
Bruce T, Seet   +9 more
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Immune evasion by adenoviruses

Immunological Reviews, 1999
Summary: .Adenovirus is a human pathogen that infects mainly respiratory and gastrointestinal epithelia. While the pathology caused by this virus is generally not life threatening in immunocompetent individuals, there is a large literature describing its ability to establish a persistent infection.
J A, Mahr, L R, Gooding
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Immune Evasion

Science's STKE, 2003
Helicobacter pylori , which infects roughly half of the world population, can cause chronic and persistent infections of the stomach that can eventually lead to chronic gastritis, gastric and duodenal ulceration, and even malignancies. Gebert et al. now show how H.
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Cytomegalovirus Immune Evasion

2008
Human cytomegalovirus (HCMV) has become a paradigm for viral immune evasion due to its unique multitude of immune-modulatory strategies. HCMV modulates the innate as well as adaptive immune response at every step of its life cycle. It dampens the induction of antiviral interferon-induced genes by several mechanisms. Further striking is the multitude of
C, Powers   +3 more
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Immune evasion by staphylococci

Nature Reviews Microbiology, 2005
Staphylococcus aureus can cause superficial skin infections and, occasionally, deep-seated infections that entail spread through the blood stream. The organism expresses several factors that compromise the effectiveness of neutrophils and macrophages, the first line of defence against infection. S.
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Immune evasion strategies of flaviviruses

Vaccine, 2013
Flavivirus is a genus of the family Flaviviridae. It includes West Nile virus (WNV), dengue virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and several other viruses which lead to extensive morbidity and mortality in humans.
Jing, Ye   +4 more
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Vaccinia virus immune evasion

Immunological Reviews, 1997
SummaryVaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include proteins which oppose apoptosis. Synthesise steroids, capture chemokines, counteract complement, interfere with interferon and intercept ...
G L, Smith   +4 more
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Immune Evasion in Ebolavirus Infections

Viral Immunology, 2015
Ebola virus (EBOV) infects humans as well as several animal species. It can lead to a highly lethal disease, with mortality rates approaching 90% in primates. Recent advances have deepened our understanding of how this virus is able to prevent the development of protective immune responses.
Jonathan, Audet, Gary P, Kobinger
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Viral Strategies of Immune Evasion

Science, 1998
The vertebrate body is an ideal breeding ground for viruses and provides the conditions that promote their growth, survival, and transmission. The immune system evolved and deals with this challenge. Mutually assured destruction is not a viable evolutionary strategy; thus, the study of host-virus interactions provides not only a glimpse of life at ...
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Pneumocystis: Immune recognition and evasion

The International Journal of Biochemistry & Cell Biology, 2006
Pulmonary infection caused by the opportunistic fungal organism Pneumocystis continues to be a leading AIDS defining illness. The initiation of highly active antiretroviral therapy (HAART) in the HIV-infected population has led to a significant reduction in the incidence of Pneumocystis pneumonia (PCP), although recent trends suggest the incidence has ...
Shannon M, Pop   +2 more
openaire   +2 more sources

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