Results 231 to 240 of about 1,940,572 (373)

Multimodal Artificial Intelligence‐Based Virtual Biopsy for Diagnosing Abdominal Lavage Cytology‐Positive Gastric Cancer

Advanced Science, EarlyView.
The multimodal AI‐based RSA model is a powerful tool for diagnosing GC‐CY1, offering significant advantages over traditional diagnostic methods. By combining radiomic and clinical data, the model achieves superior predictive performance, providing a non‐invasive, accurate, and rapid alternative for detecting peritoneal involvement in gastric cancer ...
Ping'an Ding, Jiaxuan Yang, Honghai Guo, Jiaxiang Wu, Haotian Wu, Tongkun Li, Renjun Gu, Lilong Zhang, Jinchen He, Peigang Yang, Yuan Tian, Ning Meng, Xiaolong Li, Zhenjiang Guo, Lingjiao Meng, Qun Zhao   +15 more
wiley   +1 more source

CTHRC1: a key player in colorectal cancer progression and immune evasion. [PDF]

Front Immunol
Chen Q, Wang H, Liu Q, Luo C.
europepmc   +1 more source

Synthetic Lethality of SHP2 and XIAP Suppresses Proliferation and Metastasis in KRAS‐mutant Nonsmall Cell Lung Cancer

Advanced Science, EarlyView.
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu, Yu‐wen Sheng, Zhe Fan, Zhao Wu, Ling‐yu Li, Rui‐ying Xi, Xiao‐ke Shi, Guo‐lin Zhang, Fei Wang   +8 more
wiley   +1 more source

Microbial Evasion of the Immune System: Structural Modifications of Enterobactin Impair Siderocalin Recognition [PDF]

, 2006
Rebecca J. Abergel, Evan G. Moore, Roland K. Strong, Kenneth N. Raymond   +3 more
openalex   +1 more source

The emerging role of glycolysis and immune evasion in ovarian cancer. [PDF]

Cancer Cell Int
Jin B, Miao Z, Pan J, Zhang Z, Yang Y, Zhou Y, Jin Y, Niu Z, Xu Q.   +8 more
europepmc   +1 more source

Targeting the Adenosine‐Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study presents engineered probiotics that convert immunosuppressive adenosine into inosine in tumors, alleviating immunosuppression and enhancing antitumor immunity. Demonstrating efficacy in murine ectopic and orthotopic tumor models, this approach offers a promising probiotic‐based cancer immunotherapy strategy, highlighting the potential of ...
Jinhui Wang, Jing Wang, Zhijie Yu, Hongyu Wen, Chensi Zhao, Jiayong Zhong, Chuanle Xiao, Yingqiu Li, Jianqiao Xu, Jinquan Wang, Zong‐Wan Mao, Wei Xia   +11 more
wiley   +1 more source

Human cytomegalovirus infection of cells of hematopoietic origin: HCMV-induced immunosuppression, immune evasion, and latency [PDF]

, 2006
Mariana G. Bego, Stephen St. Jeor
openalex   +1 more source

Amino acid metabolism in glioblastoma pathogenesis, immune evasion, and treatment resistance. [PDF]

Cancer Cell Int
Srivastava S, Anbiaee R, Houshyari M, Laxmi, Sridhar SB, Ashique S, Hussain S, Kumar S, Taj T, Akbarnejad Z, Taghizadeh-Hesary F.   +10 more
europepmc   +1 more source

N4‐Acetylcytidine‐Mediated CD2BP2‐DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression

Advanced Science, EarlyView.
The long non‐coding RNA (lncRNA) CD2BP2‐DT is upregulated in breast cancer and correlates with poor patient prognosis. Mechanistically, CD2BP2‐DT drives YBX1 phase separation to stabilize CDK1 and promote breast cancer progression. Moreover, NAT10‐mediated N4‐acetylcytosine (ac4C) modification further enhances CD2BP2‐DT expression.
Hongyu Wang, Bozhi Zhao, Jiayu Zhang, Qunyu Hu, Linlin Zhou, Yinghui Zhang, Yixin Cai, Yuansong Qu, Tao Jiang, Dongwei Zhang   +9 more
wiley   +1 more source

Immune system evasion by peripheral nerve sheath tumor [PDF]

, 2006
Philip R. Lee, Jonathan E. Cohen, R. Douglas Fields   +2 more
openalex   +1 more source