Results 11 to 20 of about 1,614,132 (267)
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia
Molecular Cancer, 2022 Background Chronic lymphocytic leukemia (CLL) is the most frequent, and still incurable, form of leukemia in the Western World. It is widely accepted that cancer results from an evolutionary process shaped by the acquisition of driver mutations which ...
Alejandro M. Hortal +16 more
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Sleep and immune function [PDF]
Pflügers Archiv - European Journal of Physiology, 2011 Sleep and the circadian system exert a strong regulatory influence on immune functions. Investigations of the normal sleep-wake cycle showed that immune parameters like numbers of undifferentiated naïve T cells and the production of pro-inflammatory cytokines exhibit peaks during early nocturnal sleep whereas circulating numbers of immune cells with ...
Besedovsky, Luciana +2 more
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Zinc: its impact on immune function in children
Pediatria Polska, 2022 Based on the analysis of literary sources, this review highlights the main reasons and mechanisms of zinc impact on the development of immunodeficiency conditions in children.
Maria Kinash +2 more
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Regulation of CCR7-dependent cell migration through CCR7 homodimer formation
Scientific Reports, 2017 The chemokine receptor CCR7 contributes to various physiological and pathological processes including T cell maturation, T cell migration from the blood into secondary lymphoid tissues, and tumor cell metastasis to lymph nodes.
Daichi Kobayashi +5 more
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Immune and non-immune functions of the immunoproteasome
Frontiers in Bioscience, 2012 The biological importance of the ubiquitin-proteasome system in the control of myriad cellular processes has been well-recognized; however, the pathophysiological significance of the immunoproteasome, the inducible form of the proteasome, has not been well-comprehended until lately.
Arkhjamil, Angeles +2 more
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On Correlation-immune functions [PDF]
, 2007 We establish the link between correlation-immune functions and orthogonal arrays. We give a recursive definition of any correlation-immune function of maximal degree. We describe the set of quadratic balanced correlation-immune functions of maximal order. Some constructions are then deduced.
Paul Camion +3 more
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Immune function in mania [PDF]
Biological Psychiatry, 1988 There is now a large body of evidence suggesting a close interaction between the central nervous system and the immune system. More specifically, immunological abnormalities have been described in relation to psychological stress (Jemrnott and Locke 1984) and in patients with psychiatric illness (DeLisi and Crow 1986).
Kronfol, Ziad A., House, J. Daniel
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B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments
eLife, 2019 Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto ...
Sophie I Roper +5 more
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Glutathione and immune function [PDF]
Proceedings of the Nutrition Society, 2000 The immune system works best if the lymphoid cells have a delicately balanced intermediate level of glutathione. Even moderate changes in the intracellular glutathione level have profound effects on lymphocyte functions. Certain functions, such as the DNA synthetic response, are exquisitely sensitive to reactive oxygen intermediates and, therefore, are
W, Dröge, R, Breitkreutz
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Function of immunoglobulin A in immunity [PDF]
Gut, 2000 Immunoglobulin A (IgA) is by far the most abundant immunoglobulin in humans.1 It is also the most heterogeneous. Serum IgA is mainly monomeric. It is produced by B lymphocytes in the bone marrow and in some lymphoid organs. Humans produce as much serum IgA as they do IgG. Most of the IgA in mammals is, however, found in mucosal secretions.
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