A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
Baxter, LA +60 more
core +1 more source
B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments
Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto ...
Sophie I Roper +5 more
doaj +1 more source
Metabolic regulation of regulatory T cell development and function [PDF]
It is now well established that the effector T cell (Teff) response is regulated by a series of metabolic switches. Quiescent T cells predominantly require ATP-generating processes, whereas proliferating Teff require high metabolic flux through growth ...
Marelli-Berg, F +7 more
core +1 more source
Lymphocyte activation gene-3 : the expression and function in the immune system [PDF]
Lymphocyte activation gene-3 (LAG-3) is the structural homologue of a well-known TCR co-receptor CD4. Recently, it has been suggested that LAG-3 might play a role in modulation of immune response, by being a negative regulator of T cell activation. To
Kisielow, Malgorzata
core +1 more source
The impact of a ketogenic diet on weight loss, metabolism, body composition and quality of life
Summary: A ketogenic diet (KD) is increasingly debated as a countermeasure against nutrition-related modern diseases. While being immunologically beneficial, KD is still suspected of having severe metabolic side effects and negatively impacting general ...
Simon Hirschberger +7 more
doaj +1 more source
Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function [PDF]
Background: Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens. Significant depression of the host'
Owain R Millington +14 more
core +1 more source
IntroductionIt is of great importance to find antibiotic alternatives that can improve poultry performance and enhance immunity. Plant-derived extracts and their concentrates are natural bioactive compounds that are widely and effectively applied as the ...
Xiaoshan Sun +8 more
doaj +1 more source
Suppression of adaptive immunity to heterologous antigens during plasmodium infection through hemozoin-induced failure of dendritic cell function [PDF]
Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens.
Di Lorenzo, Caterina +4 more
core +2 more sources
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source

