Results 21 to 30 of about 1,614,132 (267)

The impact of a ketogenic diet on weight loss, metabolism, body composition and quality of life

iScience
Summary: A ketogenic diet (KD) is increasingly debated as a countermeasure against nutrition-related modern diseases. While being immunologically beneficial, KD is still suspected of having severe metabolic side effects and negatively impacting general ...
Simon Hirschberger, David Effinger, Polina Yoncheva, Annika Schmid, Mara-Noel Weis, Lesca-Miriam Holdt, Daniel Teupser, Simone Kreth   +7 more
doaj   +1 more source

Effects of Yucca schidigera extract on serum biochemical parameters, humoral immune response, and intestinal health in young pigeons

Frontiers in Veterinary Science, 2023
IntroductionIt is of great importance to find antibiotic alternatives that can improve poultry performance and enhance immunity. Plant-derived extracts and their concentrates are natural bioactive compounds that are widely and effectively applied as the ...
Xiaoshan Sun, Xiaoshan Sun, Zheng Wang, Xing Li, Xing Li, Shaohua Du, Shaohua Du, Dongmei Lin, Yuxin Shao   +8 more
doaj   +1 more source

Zinc and immune function [PDF]

European Journal of Clinical Nutrition, 2002
It is well recognized that zinc is an essential trace element, influencing growth and affecting the development and integrity of the immune system. Research has begun to clarify the molecular mechanisms underlying the action of zinc on the immune function. It is clear that this trace element has a broad impact on key immunity mediators, such as enzymes,
openaire   +2 more sources

Immune functions of the esophagus

Journal of Allergy and Clinical Immunology
The esophagus has long been regarded as a simple conduit for food transport. A new paradigm now recognizes it as an immune organ actively involved in environmental sensing, antigen tolerance, and neuroimmune signaling to maintain mucosal homeostasis. The stratified squamous epithelium provides a vital physical barrier, supported by transmembrane mucins
Mark Rochman, Marc E. Rothenberg
openaire   +3 more sources

The function of immunoglobulin A in immunity [PDF]

The Journal of Pathology, 2005
AbstractThe vast surfaces of the gastrointestinal, respiratory, and genitourinary tracts represent major sites of potential attack by invading micro‐organisms. Immunoglobulin A (IgA), as the principal antibody class in the secretions that bathe these mucosal surfaces, acts as an important first line of defence.
Woof, Jenny M, Kerr, Michael A
openaire   +3 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Mitochondrial damage drives T-cell immunometabolic paralysis after major surgery

EMBO Molecular Medicine
Cytotoxic T cell (CTL) dysfunction is a hallmark of immune paralysis after major surgery, increasing susceptibility to severe nosocomial infections and contributing to mortality in critically ill patients. The mechanisms remain poorly understood.
Simon Hirschberger, Martin B Müller, Hannah Mascolo, Melissa Seitz, Stefan Nibler, David Effinger, Kun Lu, Joscha Büch, Martin Bender, Tobias Kammerer, Sven Peterß, Karin Kleigrewe, Miriam Abele, Teresa Barth, Olga Kushnir, Axel Imhof, Steffen Dietzel, Bernd Wegener, Ralf Sowa, Frank Vogel, Peter Lamm, Roland Tomasi, Kristian Unger, Markus Sperandio, Erich Kilger, Simone Kreth, Max Hübner   +26 more
doaj   +1 more source

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins, Paola de Lorenzo, Rishi S. Kotecha, Andishe Attarbaschi, Gabriele Escherich, Karsten Nysom, Jan Stary, Alina Ferster, Benoit Brethon, Franco Locatelli, Martin Schrappe, Peggy E. Scholte‐van Houtem, Maria G. Valsecchi, Rob Pieters, Inge M. van der Sluis   +14 more
wiley   +1 more source

ICAMs in Immunity, Intercellular Adhesion and Communication

Cells
Interactions among leukocytes and leukocytes with immune-associated auxiliary cells represent an essential feature of the immune response that requires the involvement of cell adhesion molecules (CAMs).
Claudia Guerra-Espinosa, María Jiménez-Fernández, Francisco Sánchez-Madrid, Juan M. Serrador   +3 more
doaj   +1 more source