Results 181 to 190 of about 443 (202)
The impact of egg adaptation and immune imprinting on influenza vaccine effectiveness
VaccineMost influenza vaccines are produced in hens' eggs and may undergo 'egg adaptation', whereby mutations within the haemagglutinin protein that result in adaptation to the avian cells undergo positive selection. It is well established that egg adaptation can impact antigenicity and vaccine effectiveness (VE) by causing mismatches between the vaccine ...
Sankarasubramanian Rajaram +2 more
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433 Loricrin imprints adaptive immunity
Journal of Investigative Dermatology, 2022Y. Ishitsuka +3 more
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Early life imprinting of intestinal immune tolerance and tissue homeostasis
Immunological ReviewsSummaryBesides its canonical role in protecting the host from pathogens, the immune system plays an arguably equally important role in maintaining tissue homeostasis. Within barrier tissues that interface with the external microenvironment, induction of immune tolerance to innocuous antigens, such as commensal, dietary, and environmental antigens, is ...
Yoselin A. Paucar Iza +1 more
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Structural Imprinting of the Cutaneous Immune Effector Function
ASEAN Journal of PsychiatryThe epidermal tissue undergoes extensive cross-linkages of the cytoskeleton, ultimately leading to the heavily disulfide cross-linked dead cell layer, the stratum corneum. Therefore, cornification is compared to the anabolic metabolism of sulfur. The leaky para cellular barrier enables antigen-presenting cells to access foreign substances easily and ...
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Maternal imprinting and determinants of neonates’ immune function in the SEPAGES mother-child cohort
Frontiers in Immunology, 2023Laurence Chaperot +2 more
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Deceptive Imprinting: Insights into Mechanisms of Immune Evasion and Vaccine Development
1999This chapter discusses insights into mechanisms of immune evasion and vaccine development. Introduction of foreign antigens into the host either by vaccination or infection in many cases leads to the production of specific antibody. Depending on the nature of the immunogen and the various pathways leading to B-cell activation, the clonality of the ...
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Early life imprinting of the immune system by the microbiota
L'empreinte du microbiote sur le système immunitaire tôt dans la vie Résumé non ...openaire +1 more source
Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
Nature, 2023Ronghua Jin +2 more
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