This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im+10 more
wiley +1 more source
SOWAHA as a Cancer Suppressor Gene Influence Metabolic Reprogramming [PDF]
SOWAHA is a protein-coding gene, also known as ANKRD43. Studies have indicated that SOWAHA can serve as a prognostic biomarker in colorectal cancer and pancreatic cancer. However, there are few reports about SOWAHA in other types of cancer and the specific mechanism of action of SOWAHA in cancer is also not clear.
arxiv
Infiltration of immune T cells in the brain of mice with herpes simplex virus-induced encephalitis
Woon Ling Chan+2 more
openalex +1 more source
Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model [PDF]
Stephanie Du Four+7 more
openalex +1 more source
Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles
A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han+9 more
wiley +1 more source
Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltration [PDF]
Tiziana Triulzi+14 more
openalex +1 more source
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García+23 more
wiley +1 more source
Antibody blockade of semaphorin 4D breaks down barriers to enhance tumoricidal immune infiltration and supports rational immunotherapy combinations [PDF]
Elizabeth E. Evans+19 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Understanding interplay of breast cancer and microenvironment is critical. Here we identified two transcriptomic subtypes and five immune infiltration patterns from RNA-seq and multiplex immunohistochemistry from 21 ER + /HER2- ILCs.
Fangyuan Chen+13 more
doaj +1 more source